Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-25T02:07:26.660Z Has data issue: false hasContentIssue false

Localization of active otosclerotic foci by tympano-cochlear scintigraphy (TCS) using correlative imaging

Published online by Cambridge University Press:  29 June 2007

Uwe H. Ross*
Affiliation:
Departments of Oto-Rhino-Laryngology, Nuclear Medicine and Neuroradiology, University of Freiburg, Germany
M. J. Reinhard
Affiliation:
Departments of Oto-Rhino-Laryngology, Nuclear Medicine and Neuroradiology, University of Freiburg, Germany
Berlis A.
Affiliation:
Departments of Oto-Rhino-Laryngology, Nuclear Medicine and Neuroradiology, University of Freiburg, Germany
*
Uwe H. Ross, M.D., Department of Oto-Rhino-Laryngology, University of Freiburg, Killianstrasse 5, D-79106 Freiburg, Germany.

Abstract

High-resolution, tympano-cochlear scintigraphy (TCS) is a useful tool for visualizing changes in labyrinthine bone metabolism in active otosclerosis in vivo. But until now, the activity patterns have mostly been rather imprecisely ascribed to the labyrinthine structures; more exactly by means of high- resolution CT (HR-CT). Experimental studies on TCS using a human temporal bone model revealed that correlative imaging of X-ray photographs and the scintigrams or superimposition with masks of the temporal bone drawn from the X-rays can facilitate the localization of small foci of about 0.5–1 mm.

Clinical applications of the visualization technique, combining functional with structural images, confirmed the benefit of this method, improving the accuracy in detection and localization of focal activity enrichment of the petrous bone in cases of active otosclerosis by means of TCS.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Presented in extracts at the Donau-Symposium of Oto-Rhino-Laryngology, Salzburg, Austria, 14—17 September 1994.

References

Bornemann, H., Hundeshagen, H., Franke, K. D. (1981) Digitale Szintigraphie des Ohres. Archiv der Ohr-NasKehlkopfheilkunde 231: 689—691.Google Scholar
Francis, M. D., Fogelman, I. (1987) 99mTc diphosphonate uptake mechanism on bone. In Bone Scanning in Clinical Practice. (Fogelman, I., ed.), Springer, Berlin, Heidelberg, New York, pp 7—17.Google Scholar
Linthicum, F. H., House, H. P., Althaus, S. R. (1973) The effect of sodium fluoride on otoscierotic activity as determined by strontium85. Annals of Otology, Rhinology and Laryngology 82: 609615.CrossRefGoogle Scholar
Ross, U. H., Laszig, R., Bornemann, H., Ulrich, C. (1993) Osteogenesis imperfecta: clinical symptoms and update findings in computed tomography and tympano-cochlear scintigraphy. Acta Otolaryngologica (Stockholm) 113: 620624.CrossRefGoogle ScholarPubMed
Siebenmann, F. (1900) Multiple Spongiosirung der Labyr inthkapsel als Sectionsbefund bei einem Fall von progres siver Schwerhorigkeit. Monatsschrift der Ohrenheilkunde 34 169.Google Scholar
Valvassori, G. E. (1993) Imaging of otosclerosis. Oto/aryngo logical Clinics of North America 26: 359371.CrossRefGoogle ScholarPubMed