Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-23T23:19:50.820Z Has data issue: false hasContentIssue false
  • English
  • Français

Local anaesthesia in flexible nasendoscopy. A comparison between cocaine and co-phenylcaine

Published online by Cambridge University Press:  29 June 2007

P. Lennox ,
J. Hern ,
M. Birchall  and
V. Lund
P. Lennox*
Affiliation:
Department of Rhinology, The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
J. Hern
Affiliation:
Department of Rhinology, The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
M. Birchall
Affiliation:
Department of Rhinology, The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
V. Lund
Affiliation:
Department of Rhinology, The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
*
Address for correspondence: Miss P. Lennox, The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London WC1 8DA. Fax: 0171 833 9480.
Get access Rights & Permissions [Opens in a new window]

Abstract

Flexible nasendoscopy is now an integral part of the diagnostic process in Otorhinolaryngology. Topical local anaesthesia is generally recommended and cocaine is usually the drug of choice in view of its concurrent vasoconstrictor action. However, it is expensive, a controlled drug and serious side effects have been reported. Co-phenylcaine forte is a new preparation which also has both local anaesthetic and vasoconstrictor properties. This study compares the efficacy of cocaine and Co-phenylcaine in flexible nasendoscopy and concludes that they provide similar local anaesthesia and vasoconstriction of the nasal mucosa. Co-phenylcaine forte can therefore be used as an alternative to cocaine in flexible nasendoscopy.

Keywords

EndoscopNoseAnaesthesialocalCocaine
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 6 , June 1996 , pp. 540 - 542
Copyright
Copyright © JLO (1984) Limited 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Campbell, J. P., Campbell, C. D., Warren, D. W., Prazma, T. U., Pilsbury, H. C. III (1992) Comparison of the vasoconstrictive effects of intranasally applied cocaine vs. xylometazoline/ lidocaine solution. Otolaryngology – Head and Neck Surgery 107: 697–700.CrossRefGoogle ScholarPubMed
Christie, J. L. (1976) Fatal consequences of local anaesthesia. Journal of Forensic Science 21: 671–679.Google Scholar
Coakley, J. F., Arthurs, G. J., Wilsher, T. K. (1993) The need for and development of a single use disposable nasal spray. Journal of Larygology and Otology 107: 20–23.Google Scholar
Ethimiou, J., Higenbottam, T., Holt, D., Cochrane, G. M. (1982) Plasma concentrations of lignocaine during fibreoptic bronchoscopy. Thorax 37: 68–71.CrossRefGoogle Scholar
Feehan, H. F., Mancusi-Ungaro, A. (1976) The use of cocaine as a topical anaesthetic in nasal surgery. A survey. Plastic and Reconstructive Surgery 57 (1): 62–65.Google Scholar
Frolund, L., Madsen, F., Mygind, N., Nielsen, N. H., Svendsen, U. G., Weeke, B. (1987) Comparison between different techniques for measuring nasal patency in a group of unselected patients. Ada Otolaryngologica Stockholm 104: 175–179.Google Scholar
Gleeson, N. J., Youlten, L. J., Shelton, D. M., Siodlak, M. Z., Eiser, N. M., Wengraf, C. L. (1986) Assessment of nasal airway patency: A comparison of four methods. Clinical Otolaryngology 11: 99–107.CrossRefGoogle ScholarPubMed
Holmstrom, M., Scadding, G. K., Lund, V. J., Darby, Y. C. (1990) Assessment of nasal obstruction. A comparison between rhinomanometry and nasal inspiratory peak flow. Rhinology 28: 191–196.Google ScholarPubMed
Jonathan, D. A., Violaris, N. S. (1988) Comparison of cocaine and lignocaine as intranasal anaesthetics. Journal of Laryngology and Otology 102: 628–629.Google Scholar
Lange, R. A., Cigarroa, R. C., Yancy, C. W. (1989) Cocaine induced coronary artery vasoconstriction. New England Journal of Medicine 321: 1557–1562.Google Scholar
McCormack, H. M., Home, D. J., Sheather, S. (1988) Clinical applications of visual analogue scales: a critical review. Psychological Medicine 18: 1007–1019.Google Scholar
Stott, S. A., Michels, M. J., Sanders, D. J., Riley, R. H. (1995) The cardiovascular effects of nasal Co-phenylcaine forte spray. Australian Journal of Hospital Pharmacy 25: 417–19.Google Scholar