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Keratin antibody localization in head and neck tissues and neoplasms

Published online by Cambridge University Press:  29 June 2007

Shan-Rong Shi
Affiliation:
Department of Otolaryngology Pathology, Massachusetts Eye and Ear Infirmary.
Atul K. Bhan
Affiliation:
James Homer Wright Pathological Laboratories, Massachusetts General Hospital.
Ben Z. Pilch
Affiliation:
Department of Otolaryngology Pathology, Massachusetts Eye and Ear Infirmary. James Homer Wright Pathological Laboratories, Massachusetts General Hospital.
Lan Bo Chen
Affiliation:
Dana-Farber Cancer Institue, Harvard Medical School.
Max L. Goodman*
Affiliation:
Department of Otolaryngology Pathology, Massachusetts Eye and Ear Infirmary. James Homer Wright Pathological Laboratories, Massachusetts General Hospital.
*
Max L. Goodman, M.D. Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, Mass. 02114, U.S.A.

Abstract

Immunohistochemical staining for keratin proteins may be useful as a diagnostic parameter in head and neck neoplasms. Our study evaluates the keratin antibody staining properties of normal tissues as well as neoplastic and non-neoplastic head and neck lesions from surgical procedures performed on 100 patients. The results indicate that the anti-keratin antibody technique can be helpful in several areas of head and neck pathology.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1984

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