Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-25T23:08:48.281Z Has data issue: false hasContentIssue false
  • English
  • Français

Intra-operative application of optical coherence tomography with an operating microscope

Published online by Cambridge University Press:  26 February 2009

T Just ,
E Lankenau ,
G Hüttmann  and
H W Pau
T Just*
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Germany
E Lankenau
Affiliation:
Institute for Biomedical Optics, University of Lübeck, Germany
G Hüttmann
Affiliation:
Institute for Biomedical Optics, University of Lübeck, Germany
H W Pau
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Germany
*
Address for correspondence: Dr Tino Just, Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Strasse 137–139, D-18057 Rostock, Germany. Fax: +49 381 494 8302 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To introduce the use of optical coherence tomography with an operating microscope for intra-operative evaluation of the human larynx.

Methods:

A specially equipped operating microscope with integrated spectral domain optical coherence tomography apparatus was used during microlaryngoscopy.

Results:

Technical improvements in optical coherence tomography equipment (e.g. pilot beam, variable focal distance, improved image quality and integration into an operating microscope) have enabled greater sensitivity and imaging speed and a non-contact approach. Spectral domain optical coherence tomography now enables a better correlation between optical coherence tomography images and histological findings. With this new technology, the precision of biopsy can be improved during microlaryngoscopy.

Conclusions:

Use of this new optical coherence tomography technology, integrated into an operating microscope, enables the surgeon to define the biopsy site location and resection plane precisely, while the optical zoom of the operating microscope can be used over the complete range.

Keywords

Optical Coherence TomographyLarynxHistologyOptical BiopsyVocal Cord
Type
Short Communications
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 9 , September 2009 , pp. 1027 - 1030
Copyright
Copyright © JLO (1984) Limited 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Wong, BJ, Jackson, RP, Guo, S, Ridgway, JM, Mahmood, U, Su, J et al. In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients. Laryngoscope 2005;115:1904–11CrossRefGoogle ScholarPubMed
2 Armstrong, WB, Ridgway, JM, Vokes, DE, Guo, S, Perez, J, Jackson, RP et al. Optical coherence tomography of laryngeal cancer. Laryngoscope 2006;116:1107–13CrossRefGoogle ScholarPubMed
3 Kraft, M, Luerssen, K, Lubatschowski, H, Glanz, H, Arens, C. Technique of optical coherence tomography of the larynx during microlaryngoscopy. Laryngoscope 2007;117:950–2CrossRefGoogle ScholarPubMed
4 Bibas, AG, Podoleanu, AG, Cucu, RG, Bonmarin, M, Dobre, GM, Ward, VM et al. 3-D optical coherence tomography of the laryngeal mucosa. Clin Otolaryngol Allied Sci 2004;29:713–20CrossRefGoogle ScholarPubMed
5 Leitgeb, RA, Hitzenberger, CK, Fercher, AF. Performance of Fourier domain vs. time domain optical coherence tomography. Opt Express 2003;11:889–94CrossRefGoogle ScholarPubMed
6 Liu, B, Brezinski, ME. Theoretical and practical considerations on detection performance of time domain, Fourier domain, and swept source optical coherence tomography. J Biomed Opt 2007;12(4):044007 (doi: 10.1117/1.2753410)CrossRefGoogle ScholarPubMed
7 Just, T, Lankenau, E, Hüttman, G, Pau, HW. Optical coherence tomography as a guide for cochlear implant surgery? In: Wong, BJ, Ilgner, JFR, eds. SPIE Photonics West. San Jose: Bellingham, 2008Google Scholar
8 Pau, HW, Lankenau, E, Just, T, Behrend, D, Hüttmann, G. Optical coherence tomography as an orientation guide in cochlear implant surgery? Acta Otolaryngol 2007;127:907–13Google ScholarPubMed
9 Pau, HW, Lankenau, E, Just, T, Hüttmann, G. Imaging of cochlear structures by optical coherence tomography (OCT). Temporal bone experiments for an OCT-guided cochleostomy technique [in German]. Laryngorhinootologie 2008;87:641–6CrossRefGoogle ScholarPubMed
10 Geerling, G, Muller, M, Winter, C, Hoerauf, H, Oelckers, S, Laqua, H et al. Intraoperative 2-dimensional optical coherence tomography as a new tool for anterior segment surgery. Arch Ophthalmol 2005;123:253–7CrossRefGoogle ScholarPubMed
11 Heermann, R, Hauger, C, Issing, PR, Lenarz, T. Application of optical coherence tomography (OCT) in middle ear surgery [in German]. Laryngorhinootologie 2002;81:400–5CrossRefGoogle ScholarPubMed
12 Vokes, DE, Jackson, R, Guo, S, Perez, JA, Su, J, Ridgway, JM et al. Optical coherence tomography-enhanced microlaryngoscopy: preliminary report of a noncontact optical coherence tomography system integrated with a surgical microscope. Ann Otol Rhinol Laryngol 2008;117:538–47CrossRefGoogle ScholarPubMed
13 Lankenau, E, Klinger, D, Winter, C, Malik, A, Müller, HH, Oelckers, S et al. Combining optical coherence tomography (OCT) with an operating microscope. In: Buzug, TM, Holz, D, Weber, S, Bongartz, J, Kohl-Bareis, M, Hartmann, U, eds. Advances in Medical Engineering. Berlin, Heidelberg: Springer, 2007:343–8CrossRefGoogle Scholar
14 Sommer, K, Lankenau, E, Thorns, C, Fedder, C, Hüttman, G, Wollenberg, B. Optical coherence tomography – a new non-invasive high resolution imaging for cancer and precancerous lesions of the upper aerodigestive tract. In: Papaspyrou, S , ed. 5th European Congress of Oto-Rhino-Laryngology Head and Neck SurgeryBologna: Medimond, 2004:401–4Google Scholar
15 Häusler, G, Lindner, MW. “Coherence radar” and “spectral radar” – new tools for dermatological diagnosis. J Biomed Opt 1998;3:21–31CrossRefGoogle Scholar