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Hyponatraemia and hypothyroidism in a previously irradiated case of carcinoma of the tongue

Published online by Cambridge University Press:  29 June 2007

N. A. Nasser  and
E. G. Lever
N. A. Nasser*
Affiliation:
Senior Registrar, Department of Oral and Maxillofacial Surgery, King's College Hospital, Denmark Hill, London, SE5 8RX.
E. G. Lever
Affiliation:
Senior Registrar, Department of Medicine, King's College Hospital, Denmark Hill, London, SE5 8RX.
*
N. A. Nasser, F.D.S. F.R.C.S. (Eng). Senior Registrar, Dept. Oral and Maxillo-facial Surgery, King's College Hospital Dental School, Denmark Hill, London SE5 8RX.
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Abstract

A case of squamous cell carcinoma of the tongue was complicated by post operative hyponatraemia. The criteria for the syndrome of inappropriate secretion of anti diuretic hormone, [ADH] (SIADH) were met but the patient remained hyponatraemic despite adequate treatment. The patient had previously received radical external radiotherapy to the neck and was found to be profoundly hypothyroid. Correction of the hypothyroid state led to clinical and biochemical recovery. The frequency of post-irradiation hypothyroidism and the possible mechanisms of hypothyroid-induced hyponatraemia are discussed

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 7 , July 1987 , pp. 685 - 688
Copyright
Copyright © JLO (1984) Limited 1987

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