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Extramedullary plasmacytoma of the larynx

Published online by Cambridge University Press:  29 June 2007

Izumi Mochimatsu ,
Mamoru Tsukuda ,
Shuji Sawaki  and
Yukio Nakatani
Izumi Mochimatsu*
Affiliation:
Department of Otorhinolaryngology, School of Medicine, Yokohama City University, Japan
Mamoru Tsukuda
Affiliation:
Department of Otorhinolaryngology, School of Medicine, Yokohama City University, Japan
Shuji Sawaki
Affiliation:
Department of Otorhinolaryngology, School of Medicine, Yokohama City University, Japan
Yukio Nakatani
Affiliation:
Division Anatomic Pathology, School of Medicine, Yokohama City University, Japan
*
Izumi Mochimatsu, M.D., Department of Otorhinolaryngology, School of Medicine, Yokohama City University, 3–9 Fukuura, Kanazawa-ku, Yokohama 236, Japan
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Abstract

A case of IgD myeloma in a 54-year-old male with a long-standing history of extramedullary plasmacytoma involving the larynx is reported.

The patient was treated with radiation therapy and laryngectomy. Twelve years later, he complained of nasal bleeding. On examination he was found to have large masses in the left nasal cavity and in the left supraclavicular region. Histological examination of both lesions showed plasmacytoma. Serum immunoglobulin studies revealed an IgD monoclonal spike of the lambda type. Bence-Jones protein was present. Using the immunoperoxidase staining technique, cytoplasmic monoclonal IgD was detected.

Keywords

Laryngeal neoplasmsPlasmocytoma
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 11 , November 1993 , pp. 1049 - 1051
Copyright
Copyright © JLO (1984) Limited 1993

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