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Epidemic typhus fever and hearing loss: a histological study

(Hallpike Collection of Temporal Bone Sections)

Published online by Cambridge University Press:  29 June 2007

I. Friedmann ,
A. Frohlich  and
A. Wright
I. Friedmann
Affiliation:
Institute of Laryngology and Otology and Northwick Park Hospital.
A. Frohlich
Affiliation:
Institute of Laryngology and Otology and Northwick Park Hospital.
A. Wright
Affiliation:
Institute of Laryngology and Otology and Northwick Park Hospital.
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Abstract

Hearing loss as a frequent complication of louse–bome epidemic typhus fever has been well documented in the reports of ENT specialists serving in both the Allied and the German armies in the last war. The present paper describes the characteristic histopathological features as noted in sections of the temporal bones from five British soldiers who died in 1944 of typhus fever during the last war in Eastern Asia. The VHIth nerve showed multiple ‘typhus nodules’ and there was extensive interstitial neuritis of the VHIth nerve and demyelination of the nerve fibres. There were also widely scattered aggregations of mononuclear cells in the inner ear.

This unique study was based on the Hallpike collection of temporal bone sections.

Keywords

Typhusepidemic louse–borneHearing lossconductivesensorineuralHistologyinner earNeuritisVIIIth cranial nerve
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 4 , April 1993 , pp. 275 - 283
Copyright
Copyright © JLO (1984) Limited 1993

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