Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-26T17:59:36.286Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of passive smoking on adult nasal respiratory mucosa

Published online by Cambridge University Press:  08 October 2013

S Elwany ,
Y H Saeed  and
I Talaat
S Elwany*
Affiliation:
Department of Otolaryngology, Alexandria Medical School, Egypt
Y H Saeed
Affiliation:
Department of Otolaryngology, Alexandria Medical School, Egypt
I Talaat
Affiliation:
Department of Pathology, Alexandria Medical School, Egypt
*
Address for correspondence: Dr Samy Elwany, 4 Kfr Abdou St # 605, Alexandria, Egypt E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

The present study aimed to investigate nasal mucosal changes in response to passive exposure to cigarette smoke.

Study design:

The study included 20 women aged 35–51 years who were scheduled for non-rhinological surgical procedures, and who had at least 10 years' prolonged passive exposure to household cigarette smoke. During surgery, two 1-mm3 biopsies of nasal mucosa were taken from the lower border of the inferior turbinate. Specimens were processed and examined with light and transmission electron microscopy.

Results:

Examination of the nasal mucosa showed several histopathological changes. The severity of structural changes increased with duration of smoke exposure. No allergic or neoplastic changes were seen.

Conclusion:

Passive exposure to cigarette smoke has a deleterious effect on the nasal respiratory mucosa. Prolonged passive smoke exposure may also induce other, significant changes not detected in the present study.

Keywords

Passive SmokingNasal MucosaHistopathology
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 10 , October 2013 , pp. 977 - 981
Copyright
Copyright © JLO (1984) Limited 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Pell, JP, Haw, S, Cobbe, S. Smoke-free legislation and hospitalizations for acute coronary syndrome. N Engl J Med 2008;359:482–91CrossRefGoogle ScholarPubMed
2Dessi, P, Sambuc, R, Movlin, G, Iedoray, V. Effect of heavy smoking on nasal resistance. Acta Otolaryngol (Stockh) 1994;114:305–10CrossRefGoogle ScholarPubMed
3Gedikondele, JS, Longo-Mbenza, B, Nzanza, JM, Luila, EL, Reddy, P, Buso, D. Nose and throat complications associated with passive smoking among Congolese school children. Afr Health Sci 2011;11:315–9Google ScholarPubMed
4Stanković, A, Nikolić, M, Arandelović, M. Exposure to environmental tobacco smoke and absence from work in women in Nis, Serbia. Cent Eur J Public Health 2012;20:24–8CrossRefGoogle ScholarPubMed
5Vinke, J, Denjan, A, Severijnen, L, Fottens, J. Passive smoking causes an ‘allergic’ cell infiltrate in the nasal mucosa of non-atopic children. Int J Pediatr Otolaryngol 1999;51:73–81CrossRefGoogle ScholarPubMed
6Nageris, B, Hadar, T, Hansen, M. The effect of passive smoking on olfaction in children. Rev Laryngol Otol Rhinol (Bord) 2002;128:89–91Google Scholar
7Usenius, T, Karja, J, Collan, Y. Squamous cell carcinoma of the tongue in children. Cancer 1987;60: 236–93.0.CO;2-W>CrossRefGoogle ScholarPubMed
8Samet, JM. Secondhand smoke: facts and lies. Salud Publica Mex 2008;50:428–34CrossRefGoogle ScholarPubMed
9Atef, A, Abo Zeid, I, Qotb, M, Gad El Rab, E. Effect of passive smoking on ciliary regeneration of nasal mucosa after functional endoscopic sinus surgery in children. J Laryngol Otol 2009;123:75–9CrossRefGoogle ScholarPubMed
10Torjussen, W, Solberg, LA, Hogeveit, A. Histopathological changes of the nasal mucosa in nickel workers. Cancer 1979;44:693–743.0.CO;2-H>CrossRefGoogle ScholarPubMed
11Agius, A, Smallman, L, Pahor, A. Age, smoking and ciliary beat frequency. Clin Otolaryngol 1998;23:227–30CrossRefGoogle ScholarPubMed
12Rogers, DF, Jeffery, PK. Inhibition of cigarette smoke induced airway secretory cell hyperplasia by indomethacin, dexamethasone, prednisolone, or hydrocortisone in the rat. Exp Lung Res 1986;10:285–98CrossRefGoogle ScholarPubMed
13Jeffery, PK. The effect of tobacco smoke, with and without phenylmethyloxadiazole (PMO) on rat bronchial epithelium: a light and electron microscopic study. J Pathol 1981;133:341–59CrossRefGoogle ScholarPubMed
14Toppozada, H, Talaat, M. Human nasal epithelium and cellular elements in chronic allergic rhinitis. ORL J Otorhinolaryngol Relat Spec 1975;37:333–43CrossRefGoogle ScholarPubMed
15Toppozada, H, Talaat, M. Tunica propria in chronic allergic rhinitis. Electron-microscopic study II. The sero-mucinous glands. ORL J Otorhinolaryngol Relat Spec 1976;38:86–98CrossRefGoogle ScholarPubMed
16Elwany, S, Bumsted, R. Ultrastructural observations on vasomotor rhinitis. ORL J Otorhinolaryngol Relat Spec 1987;49:199–205CrossRefGoogle ScholarPubMed
17Dye, JA, Adler, KB. Effects of cigarette smoke on epithelial cells of the respiratory tract. Thorax 1994;49:825–34CrossRefGoogle ScholarPubMed
18Benninger, MS. The impact of cigarette smoking and environmental tobacco smoke on nasal sinus disease: a review of the literature. Am J Rhinol 1999;13:435–8CrossRefGoogle ScholarPubMed