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Delayed brainstem auditory evoked reponses in experimental diabetes mellitus*

Published online by Cambridge University Press:  29 June 2007

N. Buller
Affiliation:
Tel Aviv, Israel
N. Laurian*
Affiliation:
Tel Aviv, Israel
I. shvili
Affiliation:
Tel Aviv, Israel
L. Laurian
Affiliation:
Tel Aviv, Israel
*
Dr. N. Laurian, Dept. of Otolaryngology, Hasharon Hospital, Petah-Tiqva 49372, Israel.

Abstract

The brainstem auditory evoked responses (BAER) were utilized for the evaluation of central neural transmission in alloxan-induced diabetes in rats. The mean latencies of waves I, III, V and the interpeak latencies III-V and I-V were prolonged in diabetic rats as compared to the same rats before alloxan administration. The incidence of abnormal BAER was more frequent in the group of rats with severe diabetes (82 per cent) than in mildly diabetic animals (42 per cent). Our results may suggest the presence of a central neuropathy in experimental diabetes, which can be detected by the method of BAER.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1986

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Footnotes

*

From the Department of Otolaryngology, Hasharon Hospital, Petah-Tiqva, and Department of Endocrinology, Ichilov Medical Center, Tel Aviv University Medical School, Israel.

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