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Comparison of cocaine and lignocaine as intranasal local anaesthetics

Published online by Cambridge University Press:  29 June 2007

D. A. Jonathan  and
N. S. Violaris
D. A. Jonathan
Affiliation:
(London)
N. S. Violaris*
Affiliation:
(London)
*
N. Violaris, FRCS, ENT Registrar, ENT Department, Greenbank Hospital, Plymouth, Devon.
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Abstract

The relative efficacy of Cocaine and Lignocaine as local anaesthetic agents in the nose were compared. Twenty-five patients undergoing bilateral intra-nasal antroscopy under local anaesthetic were used as their own controls when one nasal cavity was anaesthetised with Cocaine and the other with Lignocaine. On 56 per cent of occasions the patients experienced no difference in the level of discomfort. However, on 36 per cent of occasions Cocaine was noted to give better subjective anaesthesia as compared with 8 per cent of occasions when Lignocaine was superior.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 102 , Issue 7 , July 1988 , pp. 628 - 629
Copyright
Copyright © JLO (1984) Limited 1988

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References

Adriani, J. and Campbell, D. (1956) Fatalities following topical application of local anaesthetics to mucous membranes. Journal of the American Medical Association, 162: 1527–1530.CrossRefGoogle ScholarPubMed
Adriani, J. and Zepernick, R. (1964) Clinical effectiveness of drugs used for topical anaesthesia. Journal of American Medical Association, 188: 711–716.CrossRefGoogle Scholar
Christie, J. L. (1976) Fatal consequences of local anaesthesia. Journal of Forensic Science, 21: 671–679.CrossRefGoogle Scholar
Efthimiou, J., Higenbottam, T., Holt, D. and Cochrane, G. M. (1982) Plasma concentrations of Lignocaine during fibre-optic bronchoscopy. Thorax, 37: 68–71.CrossRefGoogle Scholar
Feehan, H. F. and Mancusi-Ungaro, A. (1976) The use of cocaine as a topical anaesthetic in nasal surgery. A survey. Plastic and Reconstructive Surgery, 57(1): 62–65.CrossRefGoogle ScholarPubMed
Johns, M. E. and Henderson, R. L. (1977) Cocaine used by the Otolaryngologist. A survey. Transactions of the American Academy of Ophthalmology and Otolaryngology, 84: 969–973.Google ScholarPubMed
Mayer, , Emil, (1924) The toxic effects following the use of local anaesthetics. Journal of American Medical Association, 82.11: 876–884.CrossRefGoogle Scholar