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Clinical study of mucosa-associated lymphoid tissue lymphomas of the head and neck

Published online by Cambridge University Press:  26 August 2011

S Hosokawa ,
J Okamura ,
Y Takizawa ,
G Takahashi ,
K Hosokawa  and
H Mineta
S Hosokawa*
Affiliation:
Department of Otolaryngology, Hamamatsu University School of Medicine, Japan
J Okamura
Affiliation:
Department of Otolaryngology, Hamamatsu University School of Medicine, Japan
Y Takizawa
Affiliation:
Department of Otolaryngology, Hamamatsu University School of Medicine, Japan
G Takahashi
Affiliation:
Department of Otolaryngology, Hamamatsu University School of Medicine, Japan
K Hosokawa
Affiliation:
Department of Otolaryngology, Hamamatsu University School of Medicine, Japan
H Mineta
Affiliation:
Department of Otolaryngology, Hamamatsu University School of Medicine, Japan
*
Address for correspondence: Dr Seiji Hosokawa, Department of Otolaryngology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku Handayama, Hamamatsu, Shizuoka 431-3192, Japan Fax: +81 53 435 2253 E-mail: [email protected]
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Abstract

Background:

Limited information is available on mucosa-associated lymphoid tissue lymphomas arising in the head and neck.

Method:

A retrospective analysis was conducted of 20 patients who were histologically diagnosed with mucosa-associated lymphoid tissue lymphoma and treated at our institution between January 1990 and December 2009.

Results:

Treatment consisted of surgical resection alone in two patients (10 per cent), surgical resection with consecutive radiotherapy in one (5 per cent), and radiotherapy alone in eight (40 per cent). Three patients (15 per cent) were treated with systemic chemotherapy, and three (15 per cent) received chemoradiotherapy. Three patients (15 per cent) were informed of the diagnosis but not treated for their condition.

Conclusion:

All of the 20 patients were still alive after a mean follow-up period of 50.8 months. Local treatment for mucosa-associated lymphoid tissue lymphoma of the head and neck should be the first choice in early-stage disease. However, prolonged follow up is important to determine these patients' long-term response to treatment.

Keywords

Lymphoma, B-Cell, Marginal ZoneOtorhinolaryngology
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 3 , March 2012 , pp. 271 - 275
Copyright
Copyright © JLO (1984) Limited 2011

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