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Clinical and prognostic aspects of laryngeal clear cell carcinoma

Published online by Cambridge University Press:  08 March 2006

Domenico Testa ,
Vieri Galli ,
Gaetano de Rosa ,
Renata Iovine ,
Stefania Staibano ,
Pasquale Somma ,
Chiara Mignogna  and
Maurizio Iengo
Domenico Testa
Affiliation:
Institute of Otolaryngology-Head and Neck Surgery, University of Naples ’Federico II’, Naples, Italy
Vieri Galli
Affiliation:
Institute of Otolaryngology-Head and Neck Surgery, University of Naples ’Federico II’, Naples, Italy
Gaetano de Rosa
Affiliation:
Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples ’Federico II’, Naples, Italy
Renata Iovine
Affiliation:
Institute of Otolaryngology-Head and Neck Surgery, University of Naples ’Federico II’, Naples, Italy
Stefania Staibano
Affiliation:
Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples ’Federico II’, Naples, Italy
Pasquale Somma
Affiliation:
Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples ’Federico II’, Naples, Italy
Chiara Mignogna
Affiliation:
Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples ’Federico II’, Naples, Italy
Maurizio Iengo
Affiliation:
Institute of Otolaryngology-Head and Neck Surgery, University of Naples ’Federico II’, Naples, Italy
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Abstract

Clear cell carcinoma (CCC) of the larynx is a rare pathological finding; only eight cases are described in the literature. It occurs in older adults and shows a predilection for men. We report the ninth observation of laryngeal CCC in the literature. We reviewed the literature and correlated the prognosis of the tumour according to its site of onset and treatment.

The literature review showed that this neoplasm is highly aggressive, with a high recurrence rate and short mean survival time; the treatment of choice is surgery, and chemo- or radiotherapy are used mainly for the treatment of recurrences.

Keywords

LarynxClear Cell CarcinomaSurgical Procedures
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 119 , Issue 12 , December 2005 , pp. 991 - 994
Copyright
© 2005 Royal Society of Medicine Press

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