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Changing trends in the incidence of juvenile nasopharyngeal angiofibroma: seven decades of experience at King George's Medical University, Lucknow, India

Published online by Cambridge University Press:  11 February 2016

A Mishra  and
S C Mishra
A Mishra*
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, King George's Medical University, Lucknow, India
S C Mishra
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, King George's Medical University, Lucknow, India
*
Address for correspondence: Dr Anupam Mishra, Department of Otolaryngology and Head and Neck Surgery, King George's Medical University, Lucknow, India E-mail: [email protected]
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Abstract

Background:

The occurrence of juvenile nasopharyngeal angiofibroma is reportedly higher in India than in some other parts of the world, and our centre has seen a four-fold increase in its occurrence across seven decades.

Methods:

This paper reports a retrospective archival analysis of 701 juvenile nasopharyngeal angiofibroma cases from 1958 to 2013, and considers probable environmental factors in an Indian context that may affect its biology and the global distribution, as reported in the literature.

Results:

A continuously progressive increase in occurrence was evident, but the rapid rise observed in the current decade was alarming. The world map of juvenile nasopharyngeal angiofibroma incidence does not reflect true global distribution given the paucity of reporting. Our centre has dealt with approximately 400 cases in the last 24 years.

Conclusion:

With the alarming increase in juvenile nasopharyngeal angiofibroma incidence, there is a need for a registry to define its epidemiology. The world literature needs to reflect the status of juvenile nasopharyngeal angiofibroma incidence in the third world as well. Environmental factors known for hormone disruptive actions may influence its occurrence. Such aspects need to be considered to plan specific prevention policies.

Keywords

Nasopharyngeal NeoplasmAngiofibromaEpidemiology
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 130 , Issue 4 , April 2016 , pp. 363 - 368
Copyright
Copyright © JLO (1984) Limited 2016 

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Footnotes

Presented at the 2014 World Cancer Congress, 3–6 December 2014, Melbourne, Australia.

References

1Lund, VJ, Stammberger, H, Nicolai, P, Castelnuovo, P, Beal, T, Beham, A et al. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl 2010;22:1–143Google Scholar
2Biswas, D, Saha, S, Bera, SP. Relative distribution of the tumours of ear, nose and throat in the paediatric patients. Int J Pediatr Otorhinolaryngol 2007;71:801–5Google Scholar
3Thompson, LDR, Head and Neck Pathology; 1. ed. Cleveland, 2006Google Scholar
4Gullane, PJ, Davidson, J, O'Dwyer, T, Forte, V. Juvenile angiofibroma: a review of the literature and a case series report. Laryngoscope 1992;102:928–33CrossRefGoogle Scholar
5El-Banhawy, OA, Ragab, A, El-Sharnoby, MM. Surgical resection of type III juvenile angiofibroma without preoperative embolization. Int J Pediatr Otorhinolaryngol 2006;70:1715–23Google Scholar
6Maran, AG, Lund, VJ. Nasal physiology. In: Maran, AG, Lund, VJ, eds. Clinical Rhinology. Stuttgart: Georg Thieme, 1990;5Google Scholar
7Shamim, AA, Ghias, K, Khan, MJ. Juvenile nasopharyngeal angiofibroma: experience at a tertiary care centre in Pakistan. J Pak Med Assoc 2013;63:134–8Google Scholar
8Mistry, RC, Qureshi, SS, Gupta, S, Gupta, S. Juvenile nasopharyngeal angiofibroma: a single institution study. Indian J Cancer 2005;42:35–9CrossRefGoogle ScholarPubMed
9Ghosh, B, Saha, S, Chandra, S, Nandi, TK, Bera, SP. Juvenile nasopharyngeal angiofibroma – three years experience. Indian J Otolaryngol Head Neck Surg 2003;55:228–33CrossRefGoogle ScholarPubMed
10Chew, CT. Nasopharynx (the postnasal space). In: Kerr, AG, Groves, J, eds. Scott-Brown's Otolaryngology, Volume IV: Rhinology, 5th edn.London, Boston, Durban, Singapore, Sydney, Toronto, Wellington: Butterworth, 1987Google Scholar
11Bhatia, ML, Mishra, SC, Prakash, J. Lateral extensions of nasopharyngeal fibroma. J Laryngol Otol 1967;81:99–106Google Scholar
12Boghani, Z, Husain, Q, Kanumuri, VV, Khan, MN, Sangvhi, S, Liu, JK et al. Juvenile nasopharyngeal angiofibroma: a systematic review and comparison of endoscopic, endoscopic-assisted, and open resection in 1047 cases. Laryngoscope 2013;123:859–69Google Scholar
13Bosraty, H, Atef, A, Aziz, M. Endoscopic vs. open surgery for treating large, locally advanced juvenile angiofibromas: a comparison of local control and morbidity outcomes. Ear Nose Throat J 2011;90:529–34Google Scholar
14Midilli, R, Karci, B, Akyildiz, S. Juvenile nasopharyngeal angiofibroma: analysis of 42 cases and important aspects of endoscopic approach. Int J Pediatr Otorhinolaryngol 2009;73:401–8Google Scholar
15Danesi, G, Panciera, DT, Harvey, RJ, Agostinis, C. Juvenile nasopharyngeal angiofibroma: evaluation and surgical management of advanced disease. Otolaryngol Head Neck Surg 2008;138:581–6CrossRefGoogle ScholarPubMed
16Pryor, SG, Moore, EJ, Kasperbauer, JL. Endoscopic versus traditional approaches for excision of juvenile nasopharyngeal angiofibroma. Laryngoscope 2005;115:1201–7CrossRefGoogle ScholarPubMed
17Witt, TR, Shah, J, Sternberg, SS. Juvenile nasopharyngeal angiofibroma: 30 year clinical review. Am J Surg 1983;146:521–5Google Scholar
18McCombe, A, Lund, VJ, Howard, DJ. Recurrence in juvenile angiofibroma. Rhinology 1990;28:97–102Google Scholar
19Singuluri, H, Sukumaran, MK. Milk adulteration in Hyderabad, India – a comparative study on the levels of different adulterants present in milk. J Chromatograph Separat Techniq 2014;5:212CrossRefGoogle Scholar
20Most Indians drinking adulterated milk, finds FSSAI survey 2012. In: http://www.downtoearth.org.in/content/most-indians-drinking-adulterated-milk-finds-fssai-survey [20 November 2014]Google Scholar