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An improved morphological technique for the study of cochleotoxicity in guinea pigs

Published online by Cambridge University Press:  29 June 2007

M. W. Yung  and
A. Wright
M. W. Yung*
Affiliation:
Department of Otorhinolaryngology, University of Liverpool.
A. Wright
Affiliation:
Institute of Laryngology and Otology, 330 Gray' Inn Road, London WC1 8EE.
*
Department of Otorthinolaryngology, University of Liverpool, Royal Liverpool Hospital, Prescot Street, Liverpool L69 3BX.
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Summary

Scanning electron microscopy is commonly used to study the normal or pathologically altered cochlear epithelium. It is especially useful for the study of ototoxicity in humans or animals. A cochlear microdissection technique in the guinea pig is presented which permits examination of the whole membranous cochlea with little artefactual damage to the sensory structures under study.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 100 , Issue 11 , November 1986 , pp. 1235 - 1244
Copyright
Copyright © JLO (1984) Limited 1986

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