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Adult nasal gliomas

Published online by Cambridge University Press:  05 February 2015

C Xie ,
S Hampal  and
C Li
C Xie*
Affiliation:
Department of ENT, Warrington Hospital, UK
S Hampal
Affiliation:
Department of ENT, Warrington Hospital, UK
C Li
Affiliation:
Department of Pathology, Warrington Hospital, UK
*
Address for correspondence: Ms C Xie, ENT Department, Warrington Hospital, Lovely Lane, Warrington WA5 1QG, UK E-mail: [email protected]
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Abstract

Background:

Nasal gliomas are congenital neurogenic tumours that are mostly diagnosed in the perinatal period. They occur in 1 in 20 000–40 000 live births. Cases reported in adulthood are rare and the management in adults is controversial.

Case report:

A 55-year-old female had an incidental diagnosis of nasal glioma after routine endoscopic sinus surgery and polypectomy. Post-operatively, there was symptomatic improvement, but it was complicated by a cerebrospinal fluid leak.

Conclusion:

Most adults who present with nasal gliomas have non-specific nasal symptoms, and diagnosis is made from an incidental finding of heterotopic glial tissue. The management of nasal gliomas in adults is contentious. In contrast, management in the paediatric population is better established and the treatment is surgical excision. The relevant literature is reviewed.

Keywords

GliomaEncephaloceleNeurogliaCerebrospinal Fluid RhinorrheaNose DiseasesParanasal Sinuses
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 129 , Issue 3 , March 2015 , pp. 288 - 292
Copyright
Copyright © JLO (1984) Limited 2015 

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Footnotes

Presented as a poster at the Royal Society of Medicine – Laryngology and Rhinology Section, 7 March 2014, London, UK.

References

1Harley, E. Paediatric congenital nasal masses. Ear Nose Throat J 1991;70:28–33Google Scholar
2Hengerer, A. Congenital Anomalies of the Nose. Alexandria, Virginia: American Academy of Otolaryngology–Head and Neck Surgery, 1987Google Scholar
3Black, BK, Smith, DE. Nasal glioma: two cases with recurrence. Arch Neurol Psychiat 1950;64:614–30Google Scholar
4Martinez-Lage, JF, Garcia-Contreras, JD, Ferri-Niguez, B, Sola, J. Nasal cerebral heterotopia: nasal atretic cephalocele. Neurocirugia (Astur) 2002;13:385–8CrossRefGoogle ScholarPubMed
5Patterson, K, Kapur, S, Chandra, RS. “Nasal gliomas” and related brain heterotopias: a pathologist's perspective. Pediatr Pathol 1986;5:353–62Google Scholar
6Morgan, D, Evans, J. Developmental nasal anomalies. J Laryngol Otol 1990;104:394–403Google Scholar
7Gorenstein, A, Kern, E. Nasal gliomas. Arch Otolaryngol 1980;106:536–40Google Scholar
8Harrison, D, Lund, V. Neuroectodermal lesion. In: Tumours of Upper Jaw. London: Churchill Livingstone, 1993;295–306Google Scholar
9Karma, P, Rasanen, O, Karaja, J. Nasal gliomas. A review and report of two cases. Laryngoscope 1976;87:1169–79Google Scholar
10Frodel, J, Larrabee, W, Raisis, J. The nasal dermoid. Otolaryngol Head Neck Surg 1989;101:393–4Google Scholar
11Hughes, G, Sharpino, G, Hunt, W, Tucker, H. Management of the congenital midline nasal mass: a review. Head Neck Surg 1980;2:222–33CrossRefGoogle ScholarPubMed
12Bradley, PJ, Singh, SD. Nasal glioma. J Laryngol Otol 1985;99:247–52CrossRefGoogle ScholarPubMed
13Smith, KR Jr, Schwartz, HG, Luse, SA, Ogura, JH. Nasal gliomas: a report of five cases with electron microscopy of one. J Neurosurg 1963;20:968–82CrossRefGoogle ScholarPubMed
14Ducic, Y. Nasal gliomas. J Otolaryngol 1999;28:285–7Google Scholar
15Pasquini, E, Farneti, G, Giausa, G, Biaviti, M. A rare case of nasal glioma in adult age. Otolaryngol Head Neck Surg 1998;6:905–6Google Scholar
16Penner, CR, Thompson, L. Nasal glial heterotopia: a clinicopathologic and immunophenotypic analysis of 10 cases with a review of the literature. Ann Diagn Pathol 2003;7:354–9Google Scholar
17Majithia, A, Liyanage, SH, Hewitt, R, Grant, WE. Adult nasal glioma presenting with visual loss. J Laryngol Otol 2010;124:1309–13Google Scholar
18Jain, RK, Shukla, PK, Aryya, NC, Srivastava, A, Kumar, S. Nasal glioma presenting as blindness in an adult. Ann Ophthalmol 2001;33:67–9Google Scholar
19Ogura, JH, Schenck, NL. Unusual nasal tumours. Otolaryngol Clin North Am 1973;6:813–37Google Scholar
20Pollard, K, Carter, DA. A case of nasal glioma and neurofibromatosis. J Laryngol Otol 1987;101:497–9Google Scholar
21Chau, HN, Hopkins, C, McGilligan, A. A rare case of nasal glioma in the sphenoid sinus of an adult presenting with meningoencephalitis. Eur Arch Otorhinolaryngol 2005;262:592–4CrossRefGoogle ScholarPubMed
22Genut, AA, Miranda, FG, Garcia, JH. Organized cerebral heterotopia in the ethmoid sinus. A case report. J Neurol Sci 1976;28:339–44Google Scholar
23Kasliwal, MK, Anand, VK, Lavi, E, Schwartz, TH. Endoscopic management of a rare case of nasal glioma in Meckel's cave in an adult: case report. Minim Invasive Neurosurg 2010;53:191–3Google Scholar
24Altissimi, G, Ascani, S, Falcetti, S, Cazzato, C, Bravi, I. Central nervous system tissue heterotopia of the nose: case report and review of the literature. Acta Otorhinolaryngol Ital 2009;29:218–21Google Scholar
25Tetzlaff, MT, Liu, P, O'Malley, BW Jr, LiVolsi, VA, Elder, D. Report of a case of sinonasal undifferentiated carcinoma arising in a background of extensive nasal gliomatosis. Head Neck 2008;30:549–55CrossRefGoogle Scholar
26Katz, A, Lewis, JS. Nasal gliomas. Arch Otolaryngol 1971;94:351–5Google Scholar
27Yeoh, GP, Bale, PM, de Silva, M. Nasal cerebral heterotopia: the so-called nasal glioma or sequestered encephalocele and its variants. Pediatr Pathol 1989;9:531–49Google Scholar
28Patterson, K, Kapur, S, Chandra, RS. ‘Nasal gliomas’ and related brain heterotopias: a pathologist's perspective. Pediatr Pathol 1986;5:353–62CrossRefGoogle ScholarPubMed
29Rahbar, R, Resto, VA, Robson, CD, Perez-Atayde, AR, Goumnerova, LC, McGill, TJ et al. Nasal glioma and encephalocele: diagnosis and management. Laryngoscope 2003;113:2069–77CrossRefGoogle ScholarPubMed