Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-23T00:34:51.788Z Has data issue: false hasContentIssue false
  • English
  • Français

Adenoid cystic carcinoma of the sinonasal tract: outcome of endonasal endoscopic surgery at five-year follow up

Published online by Cambridge University Press:  10 April 2013

B S Gendeh ,
F D Zahedi ,
H Ahmad  and
T Y Kew
B S Gendeh*
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
F D Zahedi
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
H Ahmad
Affiliation:
Otorhinolaryngology Department, Putrjaya Hospital, Malaysia
T Y Kew
Affiliation:
Department of Radiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
*
Address for correspondence: Professor Dato’ Dr Balwant Singh Gendeh, Senior Otorhinolaryngologist and Lecturer, Otorhinolaryngology-Head and Neck Surgery Department, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaakob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia Fax: +60 3 91737840 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To study the outcome of endonasal endoscopic surgery for adenoid cystic carcinoma of the sinonasal tract over a five-year follow-up period.

Design:

Retrospective analysis.

Methods:

Four consecutive patients with adenoid cystic carcinoma of the sinonasal tract, who had undergone endonasal endoscopic surgery, were reviewed regarding age at diagnosis, sex, primary site, tumour-node-metastasis staging, treatment modalities, histopathological findings, duration of follow up, distant metastases and treatment outcome.

Results:

All patients were diagnosed at an advanced stage and had post-operative adjuvant radiotherapy. Three patients underwent endoscopic endonasal resection and one endoscopic assisted craniofacial resection. The most common primary site was the ethmoid sinus (three patients). Three patients had no evidence of recurrence. One patient who had undergone partial clearance via endoscopic endonasal resection developed cervical node metastases a year after treatment; this patient also developed distant metastases.

Conclusion:

Adenoid cystic carcinoma is difficult to treat. Sinonasal tract tumours can be resected via endoscopic endonasal resection or endoscopic assisted craniofacial resection, but prolonged follow up is advisable. Radiotherapy is an important adjuvant treatment.

Keywords

Nasal CavityParanasal SinusesCarcinoma, Adenoid CysticEndoscopySurgical Procedures, OperativeRadiotherapyNeoplasm Metastasis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 5 , May 2013 , pp. 511 - 515
Copyright
Copyright © JLO (1984) Limited 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Witt, RL. Adenoid cystic carcinoma of the minor salivary glands. Ear Nose Throat J 1991;70:218–22Google ScholarPubMed
2Kim, KH, Sung, MW, Chung, PS, Rhee, CS, Park, CI, Kim, WH. Adenoid cystic carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 1994;120:721–6CrossRefGoogle ScholarPubMed
3Wiseman, SM, Popat, SR, Nestor, RR. Adenoid cystic carcinoma of the paranasal sinuses or nasal cavity: a 40-year review of 35 cases. Ear Nose Throat J 2002;81:510–17CrossRefGoogle ScholarPubMed
4Haddad, A, Enepekides, DJ, Manolidis, S, Black, M. Adenoid cystic carcinoma of the head and neck: A clinicopathologic study of 37 cases. J Otolaryngol 1995;24:201–5Google ScholarPubMed
5Spiro, RH, Huvos, AG, Strong, EW. Adenoid cystic carcinoma of salivary origin. A clinicopathologic study of 242 cases. Am J Surg 1974;128:512–20CrossRefGoogle ScholarPubMed
6Takagi, D, Fukuda, S, Furuta, Y, Yagi, K, Hamma, A, Nagahashi, T et al. Clinical study of adenoid cystic carcinoma of the head and neck. Aurus Nasus Larynx 2001;28(suppl):S99–102CrossRefGoogle ScholarPubMed
7Yousem, DM, Gad, K. Tufano, RP. Resectability issues with head and neck cancer. AJNR Am J Neuroradiol 2006;27:2024–36Google ScholarPubMed
8Spiro, RH. Salivary neoplasms: overview of a 35 year experience with 2,807 patients. Head Neck Surg 1986;8:177–84CrossRefGoogle Scholar
9Bradley, PJ. Submandibular gland and minor salivary gland neoplasms. Curr Opin Otolaryngol Head Neck Surg 1999;7:72–8CrossRefGoogle Scholar
10Kraus, DH, Roberts, JK, Medendorp, SV, Levine, HL, Wood, BG, Tucker, HM et al. Nonsquamous cell malignancies of the paranasal sinuses. Ann Otol Rhinol Laryngol 1990;99:5–11Google ScholarPubMed
11Miller, RH, Calcaterra, TC. Adenoid cystic carcinoma of the nose, paranasal sinuses, and palate. Arch Otolaryngol 1980;106:424–6CrossRefGoogle ScholarPubMed
12Leafstedt, SW, Gacta, JF, Sako, K, Adenoid cystic carcinoma of major and minor salivary glands. Am J Surg 1971;122:756–62CrossRefGoogle ScholarPubMed
13Rhee, CS, Won, TB, Lee, CH, Min, YG, Sung, MY, Kim, KH et al. Adenoid cystic carcinoma of the sinonasal tract: treatment results. Laryngoscope 2006;116:982–6CrossRefGoogle ScholarPubMed
14Sung, MW, Kim, KH, Kim, JW, Min, YG, Seong, WJ, Roh, JL et al. Clinicopathologic predictors and impact of distant metastasis from adenoid cystic carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 2003;129:1193–7CrossRefGoogle ScholarPubMed
15Prasad, U, Rampal, L. Descriptive epidemiology of nasopharyngeal carcinoma in Pennisular Malaysia. Cancer Causes Control 1992;3:179–82CrossRefGoogle ScholarPubMed
16Garden, AS, Weber, RS, Morrison, WH. The influence of positive margins and nerve invasion in adenoid cystic carcinoma of the head and neck treated with surgery and radiation. Int J Radiat Oncol Biol Phys 1995;32:619–26CrossRefGoogle ScholarPubMed
17Yousem, DM, Gad, K, Tufano, RP. Resectability issues with head and neck cancer. Am J Neurol 2006;27:2024–36Google ScholarPubMed
18Seifert, G, Sobin, LH. The World Health Organization's Histological Classification of Salivary Gland Tumours: a commentary on the second edition. Cancer 1992;70:379–853.0.CO;2-C>CrossRefGoogle ScholarPubMed
19Szanto, PA, Luna, MA, Tortoledo, ME, White, RA. Histologic grading of adenoid cystic carcinoma of the salivary glands. Cancer 1984;54:1062–93.0.CO;2-E>CrossRefGoogle ScholarPubMed
20Perzin, KH, Gullane, P, Clairmont, AC. Adenoid cystic carcinoma arising in salivary glands: a correlation of histologic features and clinical course. Cancer 1978;42:265–823.0.CO;2-Z>CrossRefGoogle ScholarPubMed
21Batsakis, JG, Luna, MA, El-Naggar, A. Histopathologic grading of salivary gland neoplasms: III. Adenoid cystic carcinoma. Ann Otol Rhinol Laryngol 1990;99:1007–9CrossRefGoogle Scholar
22Raja, RS, Jennifer, LH, Zubair, WB, Virginia, AL, Barnes, EL. Adenoid cystic carcinoma with high grade transformation (a report of 11 cases and a review of the literature). Am J Surg Pathol 2007;31:1683–94Google Scholar
23Gendeh, BS, Salina, H, Selladurai, B, Jegan, T. Endoscopic assisted craniofacial resection: a case series and post-operative outcome. Med J Malaysia 2007;62:234–7Google ScholarPubMed
24Spiro, RH, Huvos, AG, Strong, EW. Adenoid cystic carcinoma: factors influencing survival. Am J Surg 1979;138:579–83CrossRefGoogle ScholarPubMed