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Variation in resistance to haemonchosis: selection of female sheep resistant to Haemonchus contortus

Published online by Cambridge University Press:  11 April 2024

V. Hooda ,
C.L. Yadav ,
S.S. Chaudhri  and
B.S. Rajpurohit
V. Hooda
Affiliation:
Department of Veterinary Parasitology, CCS, Haryana Agricultural University, Hisar, 125004, India
C.L. Yadav
Affiliation:
Department of Veterinary Parasitology, CCS, Haryana Agricultural University, Hisar, 125004, India
S.S. Chaudhri*
Affiliation:
Department of Veterinary Parasitology, CCS, Haryana Agricultural University, Hisar, 125004, India
B.S. Rajpurohit
Affiliation:
Central Sheep Breeding Farm, Hisar 125004, India
*
Author for correspondence.
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Abstract

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Seventy female lambs (6–7 months old) which were exposed to natural infections of Haemonchus contortus were designated as responders or non-responders on the basis of 10 weekly cumulative faecal egg counts. Selected responder and non-responder lambs were treated with ivermectin, housed separately and 6 weeks post-housing, seven lambs from each group were given a trickle infection of Haemonchus contortus at 1000 L3 daily for 5 days per week up to 2 weeks and examined weekly for 10 weeks after first infection. Analysis of data revealed significantly lower mean faecal egg counts and non-significantly less weight loss in responder than non-responder lambs. Mean values of haemoglobin, packed cell volume, total serum protein and peripheral eosinophil counts were significantly higher in responders than non-responders. In contrast, serum pepsinogen concentration was significantly less in responders than in non-responders. At 10 weeks post-infection, there were fewer pathological lesions and significantly lower worm burdens in responders than in non-responders. These results demonstrate a distinct resistance in responders to Haemonchus contortus infection.

Type
Review Article
Information
Journal of Helminthology , Volume 73 , Issue 2 , February 1999 , pp. 137 - 142
Copyright
Copyright © Cambridge University Press 1999

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