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Thiabendazole Tested against the Gastro-intestinal Nematodes of British Farm Animals (excluding sheep)

Published online by Cambridge University Press:  18 November 2009

J. W. G. Leiper  and
J. Crowley
J. W. G. Leiper
Affiliation:
Research Department, Boots Pure Drug Co. Ltd., Thurgarton, Nottingham, England
J. Crowley
Affiliation:
Research Department, Boots Pure Drug Co. Ltd., Thurgarton, Nottingham, England
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Extract

Experiments involving cattle, horses, pigs and fowls are presented which are considered to give evidence that thiabendazole is highly active against the Strongyle parasites but not so active against the ascarid parasites of the digestive tract of these animals. The strongyles of cattle can be controlled with a dose of 75–100 mg./kg. and those of horses with as little as 25 mg./kg. In pigs 100 mg./kg. was very active against Oesophagostomum dentatum but this dose level was of poor efficiency against Ascaris lumbricoides. A high dose of 500 mg./kg. appeared to be necessary to control Ascaridia galli in the fowl.

Type
Research Article
Information
Journal of Helminthology , Volume 37 , Issue 1-2 , March 1963 , pp. 47 - 56
Copyright
Copyright © Cambridge University Press 1963

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References

REFERENCES

Bailey, W. S., Diamond, D. L. and Walker, D. F., 1961.—“Observations on the use of thiabendazole in sheep and cattle.” J. Parasitol., 47, (Suppl.), 40–41.Google Scholar
Brown, H. D., Matzuk, A. R., Ilves, I. R., Peterson, L. J., Harris, S. A., Sarett, L. H., Egerton, J. R., Yakstis, J. J. Campbell W. C. and Cuckler, A. C., 1961. “Antiparasitic drugs, IV. 2-(4'thiazolyl)-benzimidazole, a new anthelraintic.” J. Am. chem. Soc., 83, 1764–1768.CrossRefGoogle Scholar
Cairns, G. C., 1961.—“The efficiency of thiabendazole (M.K. 360) as an anthelmintic in sheep.” N.Z. Vet. J., 9, 147–152.Google Scholar
Cuckler, A. C., 1961.—“Thiabendazole, a new broad spectrum anthclmintic.” J. Parasit., 47, (Suppl.), 30–37.Google Scholar
Egerton, J. R., 1961.—“The effect of thiabendazole upon Ascaris and Stephanuris infections.” J. Parasit., 47, (Suppl.), 37.Google Scholar
Gordon, H. McL., 1961.—“Thiabendazole: A Highly Effective Anthelmintic for Sheep.” Nature, Lond., 191, 4796, 1409–1410.CrossRefGoogle ScholarPubMed
Hedden, S. P., 1961.—“The anthelmintic activity of thiabendazole (M.K. 360).” Aust. vet. J., 37, 264–269.Google Scholar
Muller, G. L., 1961.—“Helminth research in South Africa. IV. Field trials on thiabendazole (M.K. 360) as an anthelmintic for sheep; with a note on the assessment of diagnostic methods.” J. S. Afr. vet. med. Ass., 32, 175–180.Google Scholar
Ross, D. B., 1961.—“The Influence of Thiabendazole, a new Anthelmintic, on Weight Gain in Lambs.” Vet. Rec., 73, 1455.Google Scholar
Turk, R. D., 1962.—“Observations on Thiabendazole as an Equine Anthelmintic.” J. Amer. vet. med. Ass., 141, 240.Google Scholar