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Studies on amphistomiasis in Andhra Pradesh (India) VI. Immunization of lambs and kids with gamma irradiated metacercariae of Cercariae indicae XXVI

Published online by Cambridge University Press:  05 June 2009

Md. Hafeez  and
B. V. Rao
Md. Hafeez
Affiliation:
Department of Parasitology, College of Veterinary Science, Tirupati (A.P.), India
B. V. Rao
Affiliation:
Department of Parasitology, College of Veterinary Science, Tirupati (A.P.), India
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Abstract

The life span and the pathogenicity of amphistomes developing from Cercariae indicae XXVI (Paramphistomum epiclitum) were considerably reduced when the metacercariae were gamma-irradiated at 2krad or 3krad. The higher irradiation dose resulted in the complete absence of the flukes in infected animals. Single vaccination of lambs and kids with 3000 metacercariae irradiated at 2 krad or 3 krad stimulated a significant degree of resistance against challenge with 5000 non-irradiated metacercariae. The resistance was more pronounced in the group vaccinated with metacercariae irradiated at 3krad.

Type
Research Article
Information
Journal of Helminthology , Volume 55 , Issue 1 , March 1981 , pp. 29 - 32
Copyright
Copyright © Cambridge University Press 1981

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References

REFERENCES

Boray, J.C. (1969) Experimental fascioliasis in Australia, Advances in Parasitology, 7, 95–210.CrossRefGoogle ScholarPubMed
Dawes, B. & Hughes, D.L. (1964) Fascioliasis; the invasive stages of Fasciola hepatica in mammalian host. Advances in Parasitology, 2, 97–168.CrossRefGoogle Scholar
Erickson, D.C. (1965) The fate of gamma irradiated S. mansoni, cercariae in mice. American Journal of Tropical Medicine and Hygiene, 14, 574–578.CrossRefGoogle Scholar
Hafeez, Md. (1975) Studies on amphistomes and amphistomiasis of sheep and goats in Andhra Pradesh. M.Sc. Thesis, A.P. Agricultural University, Hyderabad.Google Scholar
Horak, I.G. (1965) The immunization of sheep, goats and cattle against amphistomes. Preliminary report. Journal of the South African Veterinary Medical Association, 36, 361–363.Google Scholar
Hughes, D.C.(1962) Reduction of the pathogenicity off. hepatica in mice by X-irradiation. Nature, 193, 1093–1094.CrossRefGoogle Scholar
Movesesijan, M., Sokolic, A., Sibalic, S. & Lapojev, O. (1967) Effect of irradiation of metacercariae on subsequent morphogenesis of F. hepatica in albino mice. Experimental Parasitology. 20, 249–254.CrossRefGoogle Scholar
Ross, J.G. (1967) Studies of immunity to Fasciola hepatica: Acquired immunity in cattle, sheep and rabbits following natural infection and vaccine procedures. Journal of Helmintliology, 41, 393–399.CrossRefGoogle ScholarPubMed
Smithers, S.R. (1962) Immunizing effect of irradiated cercariae of Schistosoma mansoni in rhesus monkeys. Nature, 194, 1146–1174.CrossRefGoogle ScholarPubMed
Sokolic, A. (1968) Immunological studies on F. hepatica clinical and immunological response in mice to injection with irradiated and normal fluke cysts. Isotopes and Radiation in Parasitology. International Atomic Energy Agency, Vienna, 93, 103–110.Google Scholar
Wikerhauser, T. (1961) Out jecaju rendgenskog zracecjama metacercarija metia F. hepatica. Veterinarski Arhiv. 31, 229–236.Google Scholar