Hostname: page-component-7bb8b95d7b-lvwk9 Total loading time: 0 Render date: 2024-10-03T23:50:33.692Z Has data issue: false hasContentIssue false
  • English
  • Français

Schistosoma japonicum infection in pregnant mice

Published online by Cambridge University Press:  11 April 2024

M. Bendixen ,
M.V. Johansen ,
J. Andreassen  and
P. Nansen
M. Bendixen*
Affiliation:
Danish Bilharziasis Laboratory, Jægersborg Allé 1D, DK-2920 Charlottenlund, Denmark Department of Population, Biology University of Copenhagen, Universitetsparken 15, DK-2100 Copenhagen, Denmark
M.V. Johansen
Affiliation:
Danish Bilharziasis Laboratory, Jægersborg Allé 1D, DK-2920 Charlottenlund, Denmark
J. Andreassen
Affiliation:
Department of Population, Biology University of Copenhagen, Universitetsparken 15, DK-2100 Copenhagen, Denmark
P. Nansen
Affiliation:
Danish Centre for Experimental Parasitology, Royal Veterinary and Agricultural University, Bülowsvej 13, DK-1870 Frederiksberg C, Denmark
*
*corresponding author: Fax: +45 77 32 77 33 E-mail: [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Ten 1-week and ten 2-weeks pregnant female NMRI mice were experimentally exposed to 70 Schistosoma japonicum cercariae. Ten littermice from each group were examined for worms by perfusion 4, 6 and 8 weeks post infection. Although the mothers (n = 15) were found infected with 15.5 ± 13.4 worms at perfusion 6 and 7 weeks post infection, no worms were found in any of the examined littermice, as well as no detection of faecal or tissue eggs. Litter sizes did not differ from control groups and all littermice were healthy. The present study therefore suggests that congenital infection with S. japonicum does not occur in percutaneously infected mice and that infection of the mother during pregnancy does not seem to affect the offspring.

Type
Research Article
Information
Journal of Helminthology , Volume 73 , Issue 3 , March 1999 , pp. 277 - 278
Copyright
Copyright © Cambridge University Press 1999

References

Björkman, N. & Dantzer, V. (1989) Placentatyper hos husdyr og forsøgsdyr. Dansk Veterinært Tidsskrift 72, 1055–1060.Google Scholar
Bjørneboe, A. & Frandsen, F. (1979) A comparison of the characteristics of two strains of Schistosoma intercalatum Fischer, 1934 in mice. Journal of Helminthology 53, 195–203.CrossRefGoogle Scholar
Sakamoto, H. (1958) The influence of schistosomiasis japonica from the gynecological aspect. Kurume Igakkai Zasshi 21, 2361–2383 (in Japanese with English abstract).Google Scholar
Smithers, S.R. & Terry, R.J. (1965) The infection of laboratory hosts with cercariae of Schistosoma mansoni and the recovery of the adult worms Parasitology 55, 695–700.CrossRefGoogle ScholarPubMed
Willingham, A.L., Johansen, M.V. & Barnes, E.H. (1998) A new technique for counting Schistosoma japonicum eggs in pig feces. South East Asian Journal of Tropical Medicine and Hygiene 29, 128–130.Google ScholarPubMed
Willingham, A.L., Johansen, M.V., Bøgh, H.O., Ito, A., Andreassen, J., Lindberg, R., Christensen, N.Ø. & Nansen, P. (1999) Congenital transmission of Schistosoma japonicum in pigs. American Journal of Tropical Medicine and Hygiene 60, 311–312.CrossRefGoogle ScholarPubMed