Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-05T05:09:45.515Z Has data issue: false hasContentIssue false
  • English
  • Français

Schistosoma haematobium in Lake Malaŵi: susceptibility and molecular diversity of the snail hosts Bulinus globosus and B. nyassanus

Published online by Cambridge University Press:  01 December 2008

J.R. Stauffer Jr ,
H. Madsen ,
B. Webster ,
K. Black ,
D. Rollinson  and
A. Konings
J.R. Stauffer Jr*
Affiliation:
School of Forest Resources, Penn State University, University Park, PA16802, USA
H. Madsen
Affiliation:
DBL Centre for Health Research and Development, Faculty of Life Science, University of Copenhagen, Thorvaldsenvej57, 1871Frederiksberg C, Denmark
B. Webster
Affiliation:
The Natural History Museum, Cromwell Road, LondonSW7 5BD, UK
K. Black
Affiliation:
School of Forest Resources, Penn State University, University Park, PA16802, USA
D. Rollinson
Affiliation:
The Natural History Museum, Cromwell Road, LondonSW7 5BD, UK
A. Konings
Affiliation:
PO Box 13608, El Paso, TX79913, USA
*
*E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Intermediate hosts of Schistosoma haematobium, the causative agent of urinary schistosomiasis, in Lake Malaŵi include: Bulinus globosus, a member of the B. africanus group and B. nyassanus, a diploid member of the B. truncatus/tropicus species complex. We compared genetic variability between isolates of S. haematobium from the southern part of the lake (Cape Maclear), where both B. globosus and B. nyassanus play a role as intermediate hosts, and isolates from the northern part, where only B. globosus is host. Data show that the S. haematobium isolates from these two areas of Lake Malaŵi cannot be distinguished using nuclear or mitochondrial sequences and are capable of cross-infections.

Type
Research Papers
Information
Journal of Helminthology , Volume 82 , Issue 4 , December 2008 , pp. 377 - 382
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Brown, D.S. (1994) Freshwater snails of Africa and their medical importance. 2nd edn. London, Taylor & Francis.CrossRefGoogle Scholar
Cetron, M.S., Chitsulo, L., Sullivan, J.J., Pilcher, J., Wilson, M., Noh, J., Tsang, V.C., Hightower, A.W. & Addiss, D.G. (1996) Schistosomiasis in Lake Malawi. Lancet 348, 1274–1278.CrossRefGoogle ScholarPubMed
Harries, A.D., Fryatt, R., Walker, J., Chiodini, P.L. & Bryceson, A.D. (1986) Schistosomiasis in expatriates returning to Britain from the Tropics: a controlled study. Lancet i, 86–88.CrossRefGoogle Scholar
Jørgensen, A., Jørgensen, L.V.G., Kristensen, T.K., Madsen, H. & Stothard, J.R. (2007) Molecular phylogenetic investigations of Bulinus (Gastropoda: Planorbidae) in Lake Malaŵi with comments on the topological incongruence between DNA loci. Zoologica Scripta 36, 577–585.CrossRefGoogle Scholar
Madsen, H., Bloch, P., Kristensen, T.K. & Furu, P. (2001) Bulinus nyassanus is intermediate host for Schistosoma haematobium in Lake Malaŵi. Annals of Tropical Medicine and Hygiene 95, 353–360.Google ScholarPubMed
Pollner, J.H., Schwartz, A., Kobrine, A. & Parenti, D.M. (1994) Cerebral schistosomiasis caused by Schistosoma haematobium: case-report. Clinical Infectious Diseases 18, 354–357.CrossRefGoogle ScholarPubMed
Rollinson, D., Stothard, J.R. & Southgate, V.R. (2001) Interactions between intermediate snail hosts of the genus Bulinus and schistosomes of the Schistosoma haematobium group. Parasitology 123, S245–S260.CrossRefGoogle ScholarPubMed
Southgate, V.R., de-Clercq, D., Sene, M., Rollinson, D., Ly, A. & Vercruysse, J. (2000) Observations on the compatibility between Bulinus spp. and Schistosoma haematobium in the Senegal River basin. Annals of Tropical Medicine and Parasitology 94, 157–164.CrossRefGoogle ScholarPubMed
Stauffer, J.R. Jr, Arnegard, M.E., Cetron, M., Sullivan, J.J., Chitsulo, L.A., Turner, G.F., Chiotha, S. & McKaye, K.R. (1997) The use of fish predators to control vectors of parasitic disease: schistosomiasis in Lake Malaŵi — a case history. BioScience 47, 41–49.CrossRefGoogle Scholar
Stauffer, J.R. Jr, Madsen, H., McKaye, K., Konings, A., Bloch, P., Fereri, C., Likongwe, J. & Makaula, P. (2006) Schistosomiasis in Lake Malaŵi: relationship of fish and intermediate host density to prevalence of human infection. EcoHealth 3, 22–27.CrossRefGoogle Scholar
Stothard, J.R., Bremond, P., Andriamaro, L., Sellin, B., Sellin, E. & Rollinson, D. (2001) Bulinus species on Madagascar: molecular evolution, genetic markers and compatibility with Schistosoma haematobium. Parasitology 123, S261–S275.CrossRefGoogle ScholarPubMed
Whitworth, J.A.G. (1993) Schistosomiasis - may be contracted through swimming in Lake Malaŵi. British Medical Journal 307, 936.CrossRefGoogle ScholarPubMed