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Pulmonary superoxide dismutase activity in the mouse infected with Ancylostoma caninum larvae

Published online by Cambridge University Press:  05 June 2009

A. B. Kulkarni ,
M. K. Bhopale  and
K. D. Sharma
A. B. Kulkarni
Affiliation:
Departments of Biochemistry and Zoonosis, Haffkine Institute, Parel, Bombay 400 012, India
M. K. Bhopale
Affiliation:
Departments of Biochemistry and Zoonosis, Haffkine Institute, Parel, Bombay 400 012, India
K. D. Sharma
Affiliation:
Departments of Biochemistry and Zoonosis, Haffkine Institute, Parel, Bombay 400 012, India
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Abstract

Albino mice were infected per os with 1000 infective larvae of Ancylostoma caninum and pulmonary superoxide dismutase activity was studied after completion of lung migration. The total superoxide dismutase activity per mg of lung protein was elevated by 15% in infected mice. Of the two forms of superoxide dismutases studied, that containing Cu-Zn was elevated by 44%. this suggests that A. caninum in mice may result in histopathological changes leading to transient pulmonary oxygen toxicity.

Type
Research Note
Information
Journal of Helminthology , Volume 57 , Issue 3 , September 1983 , pp. 237 - 239
Copyright
Copyright © Cambridge University Press 1983

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References

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