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Patterns of epidemiology and control of onchocerciasis in West Africa

Published online by Cambridge University Press:  05 June 2009

B. Boatin ,
D.H. Molyneux ,
J.M. Hougard ,
O.W. Christensen ,
E.S. Alley ,
L. Yameogo ,
A. Seketeli  and
K.Y. Dadzie
B. Boatin
Affiliation:
World Health Organization, Onchocerciasis Control Programme, BP 549, Ouagadougou, Burkina Faso:
D.H. Molyneux*
Affiliation:
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK:
J.M. Hougard
Affiliation:
World Health Organization, Onchocerciasis Control Programme, BP 549, Ouagadougou, Burkina Faso:
O.W. Christensen
Affiliation:
World Health Organization, OCP Liaison Office, 1211 Geneva 27, Switzerland
E.S. Alley
Affiliation:
World Health Organization, Onchocerciasis Control Programme, BP 549, Ouagadougou, Burkina Faso:
L. Yameogo
Affiliation:
World Health Organization, Onchocerciasis Control Programme, BP 549, Ouagadougou, Burkina Faso:
A. Seketeli
Affiliation:
World Health Organization, Onchocerciasis Control Programme, BP 549, Ouagadougou, Burkina Faso:
K.Y. Dadzie
Affiliation:
World Health Organization, Onchocerciasis Control Programme, BP 549, Ouagadougou, Burkina Faso:
*
*Author for correspondence.
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Abstract

This paper summarizes the work of the Onchocerciasis Control Programme (OCP) in West Africa, a programme which over a 22 year history has reduced the public health problems of blinding onchocerciasis in eleven countries of West Africa through vector control and, more recently, ivermectin distribution. The paper emphasizes the different approaches to control the programme has developed in the different parts of the programme area which have been determined by the epidemiology of the disease (savanna/forest form), the migratory characteristics of the vectors, intensity of the disease before commencement of treatment, the combined impact of vector control and ivermectin and the likelihood of infiltration of infective blackflies from outside the programme area. The programme has constantly monitored the impact of operations on the trends in prevalence, incidence, annual transmission potential, ocular morbidity and species of fly populations, and as a result, has identified areas where special interventions are required until the programme comes to an end in 2002. The paper illustrates the changes in intensity of infection as measured by community microfilarial load and annual transmission potential over the duration of the programme control activities. The paper also defines and justifies the control strategies in different areas and identifies areas for special interventions.

Type
Symposium Papers
Information
Journal of Helminthology , Volume 71 , Issue 2 , June 1997 , pp. 91 - 101
Copyright
Copyright © Cambridge University Press 1997

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References

Boakye, D. A., Post, R. J., Mosha, F. W., Surtees, D. P. & Baker, R. H. A. (1993) Cytotaxonomic revision of the Simulium sanctipauli subcomplex (Diptera: Simuliidae) in Guinea and the adjacent countries including description of the two new species. Bulletin of Entomological Research 83, 171–186.CrossRefGoogle Scholar
Crosskey, R. W. (1987) A taxa summary for the Simulium damnosum complex, with special reference to distribution outside the control areas of West Africa. Annals of Tropical Medicine and Parasitology 81, 181–192.CrossRefGoogle ScholarPubMed
Dadzie, K. Y., De Sole, G. & Remme, J. (1992) Occular onchocerciasis and the intensity of infection in the community. IV. The degraded forest of Sierra Leone. Tropical Medicine and Parasitology 43, 75–79Google Scholar
De Sole, G., Baker, R., Dadzie, Y.D., Giese, J., Guillet, P., Keita, F.M. & Remme, J. (1991) Onchocerciasis distribution and severity in five West African countries. Bulletin of the World Health Organization 69, 689–698.Google ScholarPubMed
De Sole, G., Accorsi, A., Creusvaux, H., Giese, J., Keita, F.M. & Remme, J. (1993) Distribution of onchocerciasis in selected river basins of four West African countries. Tropical Medicine and Parasitology 44, 159–164.Google ScholarPubMed
Duke, D. O. L., Lewis, D. J. & Moore, P. J. (1966) Onchocerca-Simulium complexes I. Transmission of forest and Sudan savanna strains of Onchocerca volvulus from Cameroon by Simulium damnosum from various West African bioclimatic zones. Annals of Tropical Medicine and Parasitology 60, 318–336.CrossRefGoogle ScholarPubMed
Garms, R., Walsh, J. F. & Davies, J. B. (1979) Studies on the reinvasion of the Onchocerciasis Control Programme in the Volta River basin by Simulium damnosum s.l. with emphasis on the south western areas. Tropenmedizin und Parasitologie 30, 345–362.Google Scholar
Habbema, J.D.F., Alley, E. S., Plaisier, A. P., Van Oortmarssen, G.J. & Remme, J.H.F. (1992) Epidemiological modelling for Onchocerciasis control. Parasitology Today 8, 99–103.CrossRefGoogle ScholarPubMed
Le Berre, R., Walsh, J. F., Phillipon, B., Poudiougo, P., Henderickx, J. E. E., Guillet, P., Seketeli, A., Quillévéré, D., Grunewald, J. & Cheke, R. A. (1990) The Onchocerciasis Control Programme: retrospect and prospects. Philosophical Transactions of the Royal Society London B 328, 721–729.Google Scholar
Molyneux, D. H. (1995) Onchocerciasis control in West Africa: current status and future of the Onchocerciasis Control Programme. Parasitology Today 11, 399–402.CrossRefGoogle Scholar
O-Now, (1990) Proceedings of the Symposium on Onchocerciasis, Leiden, The Netherlands, 481 pp.Google Scholar
Plaisier, A. P. (1996) Modelling Onchocerciasis transmission and control. 181 pp. PhD thesis, Erasmus University, Rotterdam.Google Scholar
Remme, J. H. F. (1995) The African Programme for Onchocerciasis Control: preparing to launch. Parasitology Today 11, 403–406CrossRefGoogle Scholar
Samba, E. M. (1994) The Onchocerciasis Control Programme in West Africa. An example of effective public health management. 107 pp. WHO, Geneva.Google Scholar
Trees, A.J. (1992) Onchocerca ochengi: mimic, model or modulator of O. volvulus. Parasitology Today 8, 337–339.CrossRefGoogle ScholarPubMed
Webbe, G. (1992) The Onchocerciasis Control Programme. Transactions of the Royal Society of Tropical Medicine and Hygiene 86, 113–114.CrossRefGoogle ScholarPubMed
World Health Organization (1995) Onchocerciasis and its control. Report of a WHO Expert Committee Technical Report Series 852, 103 pp.Google Scholar
World Health Organization (1997) Twenty years of Onchocerciasis control in West Africa. Review of the work the Onchocerciasis Control Programme in West Africa from 1974–1994. Published by the World Health Organization.Google Scholar
Zimmerman, P. A., Dadzie, Y. D., De Sole, G., Remme, J., Alley, E. S. & Unnasch, T. R. (1992) Onchocerca volvulus DNA probe classification correlates with epidemiological patterns of blindess. Journal of Infectious Diseases 165, 964–968.CrossRefGoogle Scholar