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The mouse as a suitable host for an isolate of Schistosoma haematobium from Niger

Published online by Cambridge University Press:  05 June 2009

D. Imbert-Establet ,
C. Vera ,
B. Sellin  and
J. Jourdane
D. Imbert-Establet
Affiliation:
Laboratoire de Biologie Animale, Centre de Biologie et d'ecologie Tropicale et Méditerranéenne, U.R.A. CNRS 698, Université, Avenue de Villeneuve, 66860 Perpignan Cedex, France
C. Vera
Affiliation:
Laboratoire des schistosomoses O.C.C.G.E.–O.R.S.T.O.M., B.P. 10887 Niamey, Niger
B. Sellin
Affiliation:
Laboratoire des schistosomoses O.C.C.G.E.–O.R.S.T.O.M., B.P. 10887 Niamey, Niger
J. Jourdane
Affiliation:
Laboratoire de Biologie Animale, Centre de Biologie et d'ecologie Tropicale et Méditerranéenne, U.R.A. CNRS 698, Université, Avenue de Villeneuve, 66860 Perpignan Cedex, France
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Abstract

The host-parasite relationships of a Schistosoma haematobium isolate, originating from Niger, and the white mouse are described. Swiss OF1 albino mice were exposed individually to 200 cercariae and worms were recovered 9, 12, 16 and 20 weeks post infection. The mean worm returns ranged between 10·54 and 13·5% and did not alter significantly between 9 and 20 weeks post infection. The sex ratio of worms was always in favour of males; from 7·9:1 at 9 weeks after infection it decreased regularly to 3·28:1 at 20 weeks. Male worms reached a mean length of 8·72 mm at 20 weeks. From the 12th week post infection, a high number of eggs was found in the liver and gut. At 20 weeks, eggs were also found in the bladder. Viable eggs and infective miracidia were obtained. The infection of Bulinus truncatus from Niger succeeded with a mean rate of 61% after the first passage through mice. The isolate of S. haematobium was maintained in the laboratory during 3 successive passages through mice. These entirely new results are very probably linked to genetic characteristics peculiar to the S. haematobium populations from Niger.

Keywords

Schistosoma haematobiummousemiracidium infectivityNigerhost-parasite relationshipsTrematoda
Type
Research Article
Information
Journal of Helminthology , Volume 66 , Issue 1 , March 1992 , pp. 1 - 6
Copyright
Copyright © Cambridge University Press 1992

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