Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-25T05:54:19.064Z Has data issue: false hasContentIssue false
  • English
  • Français

The mechanisms which affect the periodic cycle of Pacific Wuchereria bancrofti microfilariae

Published online by Cambridge University Press:  18 November 2009

F. Hawking ,
Tinousi Jennings ,
F. J. Louis  and
E. Tuira
F. Hawking
Affiliation:
LBJ Tropical Medical Center, Pago Pago, American Samoa and Institut de Recherches Mėdicates “Louis Malarde”, Papeete, Tahiti
Tinousi Jennings
Affiliation:
LBJ Tropical Medical Center, Pago Pago, American Samoa and Institut de Recherches Mėdicates “Louis Malarde”, Papeete, Tahiti
F. J. Louis
Affiliation:
LBJ Tropical Medical Center, Pago Pago, American Samoa and Institut de Recherches Mėdicates “Louis Malarde”, Papeete, Tahiti
E. Tuira
Affiliation:
LBJ Tropical Medical Center, Pago Pago, American Samoa and Institut de Recherches Mėdicates “Louis Malarde”, Papeete, Tahiti
Get access Rights & Permissions [Opens in a new window]

Abstract

1. Investigations were made of the effect of various procedures in raising or lowering the microfilaria count of Pacific type Wuchereria bancrofti in the peripheral blood.

2. Raising the body temperature in the early morning was followed by a moderate fall in the counts. Breathing increased oxygen, or reduced oxygen (hypoxia) or increased carbon dioxide, or the ingestion of sodium bicarbonate produced no consistent and significant changes in the count. Ingestion of glucose (in one volunteer) was followed by a small rise in the count. Muscular exercise was followed by a fall in the count, which is interpreted as probably being a response to a lower concentration of oxygen in the venous blood returning to the lung.

3. It has not been possible to identify the physiological components of the circadian rhythm of the human body which entrain the cycle of these microfilariae. Attempts to obtain evidence incriminating the stimuli described above have been unsuccessful.

Type
Research Article
Information
Journal of Helminthology , Volume 55 , Issue 2 , June 1981 , pp. 95 - 100
Copyright
Copyright © Cambridge University Press 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Edeson, J. F. B.Hawking, F. & Symes, C. B. (1957) The periodicity of microfilariae. VI. The response of microfilariae of Wuclwrerui inaluyi and W. bancrofti. Pacific type, to various stimuli. Transactions of the Royal Society of Tropical Medicine and Hygiene, 51, 359–365.CrossRefGoogle Scholar
Hawking, F. (1967) The 24 hour periodicity of microfilariae: biological mechanisms responsible for its production and control. Proceedings of the Royal Society B, 169, 59–76.Google Scholar
Hawking, F. (1975) Circadian and other rhythms of parasites. Advances in Parasitology, 12, 123–182.CrossRefGoogle Scholar
Rosen, L. (1955) Observations on the epidemiology of human filariasis in French Oceania. American Journal of Hygiene, 61, 219–248.Google Scholar