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Larvicidal effect of flubendazole on Angiostrongylus cantonensis in mice with various worm burdens

Published online by Cambridge University Press:  05 June 2009

Jun Maki
Affiliation:
Department of Parasitology, Kitasato University School of Medicine, Sagamihara, Kanagawa-Ken, 228, Japan
Toshio Yanagisawa
Affiliation:
Department of Parasitology, Kitasato University School of Medicine, Sagamihara, Kanagawa-Ken, 228, Japan

Abstract

Flubendazole given orally at 50mg kg to mice inoculated with 50, 250 or 500 larvae of Angiostrongylus cantonensis showed almost complete larvicidal effect, irrespective of the worm burden.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1985

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References

REFERENCES

Alicata, J. E. (1965) Biology and distribution of the rat Iungworm, Angiostrongylus cantonensis and its relationship to eosinophilic meningoencephalitis and other neurological disorders of man and animals. In Advances in Parasitology, Vol. 3 (editor Dawes, B.) pp. 223248. Academic Press: London and New York.Google Scholar
Kojima, S., Hata, H., Kobayashi, M., Yokogawa, M., Takahashi, N, Takaso, T. & Kaneda, J. (1979) Eosinophilic meningitis: A suspected case of angiostrongylosis found in Shizuoka Prefecture. Honshu, Japan. American Journal of Tropical Medicine and Hygiene, 28, 3641.CrossRefGoogle ScholarPubMed
Maki, J. & Yanagisawa, T. (1980) Acid phosphatase activity demonstrated in the nematodes, Dirofilaria immitis and Angiostrongylus cantonensis with special reference to the characters and distribution. Parasitology, 80, 2338.CrossRefGoogle Scholar
Otsuru, M. (1978) Angiostrongylus cantonensis and angiostrongyliasis in Japan with those of neighboring Taiwan. Progress of Medical Parasitology in Japan, 6, 227274:Google Scholar
Yii, C. Y. (1976) Clinical observations on eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis on Taiwan. American Journal of Tropical Medicine and Hygiene, 25, 233249.CrossRefGoogle ScholarPubMed