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Immunological regulation of Angiostrongylus cantonensis infections in rats: modulation of population density and enhanced parasite growth following one or two superimposed infections

Published online by Cambridge University Press:  05 June 2009

W. K. Yong  and
Colin Dobson
W. K. Yong
Affiliation:
Department of Parasitology, University of Queensland, St. Lucia 4067 Qld, Australia
Colin Dobson
Affiliation:
Department of Parasitology, University of Queensland, St. Lucia 4067 Qld, Australia
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Abstract

Rats acquired a degree of protective immunity to reinfection with Angiostrongylus cantonensis after a single infection with 50 infective larvae. Infected rats resisted the establishment of most challenging larvae and protective immunity increased with subsequent reinfections. Part of the primary infection was lost after a superimposed second and also following a superimposed third infection, but the total size of the concurrent adult worm populations remained the same as that from a primary infection. Worms surviving from the primary infection showed enhanced growth after each reinfection but their fecundity was impaired.

Type
Research Papers
Information
Journal of Helminthology , Volume 57 , Issue 2 , June 1983 , pp. 155 - 165
Copyright
Copyright © Cambridge University Press 1983

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