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Fasciola hepatica infection in cattle and the use of simulation models for endemic areas

Published online by Cambridge University Press:  10 September 2020

M.B. Molento Open the ORCID record for M.B. Molento [Opens in a new window] ,
L.H. Dutra Open the ORCID record for L.H. Dutra [Opens in a new window] ,
I.C. Pritsch Open the ORCID record for I.C. Pritsch [Opens in a new window] ,
V.P. Garbin Open the ORCID record for V.P. Garbin [Opens in a new window] ,
A.M. Pereira ,
A. Gavião ,
A.L. Gabriel ,
R.S. de Sousa Open the ORCID record for R.S. de Sousa [Opens in a new window]  and
J.G.A. Viana Open the ORCID record for J.G.A. Viana [Opens in a new window]
M.B. Molento*
Affiliation:
Laboratory of Veterinary Clinical Parasitology, Federal University of Paraná, UFPR, Rua dos Funcionarios, 1540, Curitiba, PR, Brazil
L.H. Dutra
Affiliation:
Ministry of Health, EPISUS, Esplanada dos Ministérios, Bloco G. Brasilia, DF, Brazil
I.C. Pritsch
Affiliation:
Laboratory of Veterinary Clinical Parasitology, Federal University of Paraná, UFPR, Rua dos Funcionarios, 1540, Curitiba, PR, Brazil
V.P. Garbin
Affiliation:
Laboratory of Veterinary Clinical Parasitology, Federal University of Paraná, UFPR, Rua dos Funcionarios, 1540, Curitiba, PR, Brazil
A.M. Pereira
Affiliation:
Department of Preventive Veterinary Medicine, Federal University of Santa Maria, Avenida Roraima, 1000, Santa Maria, Brazil
A. Gavião
Affiliation:
Agricultural Office of the State of Rio Grande do Sul, Rua Bento Gonçalves, 335, Itaqui, RS, Brazil
A.L. Gabriel
Affiliation:
Department of Preventive Veterinary Medicine, Federal University of Santa Maria, Avenida Roraima, 1000, Santa Maria, Brazil
R.S. de Sousa
Affiliation:
Laboratory of Animal Pathology, Federal University of Parana, UFPR, Rua dos Funcionarios, 1540, Curitiba, PR, Brazil
J.G.A. Viana
Affiliation:
Campus Santana do Livramento, Federal University of the Pampa, Santana do Livramento, RS, Brazil
*
Author for correspondence: M.B. Molento, E-mail: [email protected]
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Abstract

Fasciolosis is a food-borne disease that causes great distress to a range of hosts, including humans. The objectives of this study were to (1) evaluate the liver damage and carcass weight of cattle naturally infected with Fasciola hepatica from the state of Rio Grande do Sul (RS), Brazil, and to (2) determine the distribution of adult flukes in 12,236 cattle liver from RS. The data from these experiments were used to calculate the overall economic loss due to F. hepatica infection. Eighteen adult Polled Hereford cows were divided into a triclabendazole (TbG) and a F. hepatica-positive group (FhG). For Experiment 1, a generalized linear mixed model revealed a statistical difference in carcass weight (49.8 kg) between TbG and FhG. The Monte Carlo analysis also revealed that the animals’ weight differences were due to the disease. For Experiment 2, the prevalence of infected livers was above 16% (1904/12,236), mostly (20.1%) from the south-west region of RS. The Susceptible-infected-recovered (SIR) epidemic model revealed the evolution of the infection using a high infectivity and low recovery rate. Other distinctive scenarios that occur in RS were also established with different rates of infectivity. The economic assessment showed a potential loss of US$45 million to the beef cattle industry of RS, with an overall State cost of US$90.3 million. These novel findings reveal the importance of fasciolosis infection, which can cause a significant health condition and poor animal welfare.

Keywords

Fasciolosishistopathologylivertrematodecattle welfarerisk analysis
Type
Research Paper
Information
Journal of Helminthology , Volume 94 , 2020 , e185
Copyright
Copyright © The Author(s), 2020. Published by Cambridge University Press

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