Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-03T05:22:25.316Z Has data issue: false hasContentIssue false
  • English
  • Français

Epidemiology of alveolar echinococcosis in southern Cantal, Auvergne region, France

Published online by Cambridge University Press:  12 April 2024

J.-F. Magnaval ,
C. Boucher ,
B. Morassin ,
F. Raoul ,
F. Raoul ,
C. Duranton ,
P. Jacquiet ,
P. Giraudoux ,
D.A. Vuitton  and
R. Piarroux
J.-F. Magnaval*
Affiliation:
Service de Parasitologie, CHU Rangueil, 31059, Toulouse, 9, France
C. Boucher
Affiliation:
Laboratoire de Parasitologie, Ecole Nationale Vétérinaire, 23 chemin des Capelles, 31073, Toulouse, France
B. Morassin
Affiliation:
Service de Parasitologie, CHU Rangueil, 31059, Toulouse, 9, France
F. Raoul
Affiliation:
Laboratoire de Biologie Environnementale, EA3194 u.s.c. INRA, Université de Franche-Comté, Place Leclerc, 25030, Besançon, France WHO Collaborating Center for Prevention and Treatment of Human Echinococcoses, 25000, Besançon, France
F. Raoul
Affiliation:
Laboratoire de Biologie Environnementale, EA3194 u.s.c. INRA, Université de Franche-Comté, Place Leclerc, 25030, Besançon, France WHO Collaborating Center for Prevention and Treatment of Human Echinococcoses, 25000, Besançon, France
C. Duranton
Affiliation:
Laboratoire de Parasitologie, Ecole Nationale Vétérinaire, 23 chemin des Capelles, 31073, Toulouse, France
P. Jacquiet
Affiliation:
Laboratoire de Parasitologie, Ecole Nationale Vétérinaire, 23 chemin des Capelles, 31073, Toulouse, France
P. Giraudoux
Affiliation:
Laboratoire de Biologie Environnementale, EA3194 u.s.c. INRA, Université de Franche-Comté, Place Leclerc, 25030, Besançon, France WHO Collaborating Center for Prevention and Treatment of Human Echinococcoses, 25000, Besançon, France
D.A. Vuitton
Affiliation:
WHO Collaborating Center for Prevention and Treatment of Human Echinococcoses, 25000, Besançon, France
R. Piarroux
Affiliation:
Service de Parasitologie, CHU Jean-Minjoz, 25000, Besançon, France WHO Collaborating Center for Prevention and Treatment of Human Echinococcoses, 25000, Besançon, France
*
*Fax: 33 5 61 14 59 72, Email , [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Alveolar echinococcosis (AE) is a helminth zoonosis which is encountered only in the northern hemisphere. In central France, the Auvergne region represents the most western and southern extension of this helminthiasis. In 1999, a human case of AE was diagnosed in the southern part of the Cantal department, where AE was supposed absent, and an epidemiological survey was subsequently carried out. The transmission of the zoonosis in the sylvatic and peridomestic definitive hosts was studied, as well as that in the rodent and human intermediate hosts. Eleven red foxes (Vulpes vulpes) were shot, and 50 fox faecal deposits were collected. Twelve farm dogs had their faeces taken by rectal touch, and four were checked after arecoline purgation. Optical detection of Echinococcus multilocularis worms was achieved on fox intestines after scraping, and also on dog stools after arecoline therapy. Coproantigen ELISA assay was performed for the 11 scraping products, for the 50 fox faeces, and for the 12 dog faecal samples. No adult AE agent was observed by microscopy, and the ELISA assay yielded positive results in one of 11 fox intestines, one of 50 fox faeces, and 2 of 12 dog faecal samples. Twenty-five small mammals were trapped, of which 19 were Arvicola terrestris water voles. One rodent liver exhibited a hepatic lesion consistent with AE. An epidemiological questionnaire was completed in 85 human volunteers, who were also serologically tested for AE. Only one (the case's husband) exhibited a Western-blotting pattern indicative of a low-grade AE infection. The results of this preliminary study suggested a slow AE extension to the south of Cantal department from the northern focus.

Type
Review Article
Information
Journal of Helminthology , Volume 78 , Issue 3 , September 2004 , pp. 237 - 242
Copyright
Copyright © Cambridge University Press 2004

References

Dabis, F., Drücker, J. & Moren, A. (1992) Epidémiologie d'intervention. 587 pp. Paris, Arnette.Google Scholar
Deblock, S. & Pétavy, A.-F. (1983) Les larves hépatiques de cestodes parasites du grand campagnol Arvicola terrestris en Auvergne (France). Annales de Parasitologie Humaine et Comparée 58, 423–437.CrossRefGoogle ScholarPubMed
Delattre, P., Pascal, M., Le Pesteur, M.H., Giraudoux, P. & Damange, J.P. (1988) Caractéristiques écologiques et épidémiologiques de l’ Echinococcus multilocularis au cours d'un cycle complet des populations d'un hôte intermédiaire (Microtus arvalis) . Canadian Journal of Zoology 66, 2740–2750.CrossRefGoogle Scholar
Delattre, P., Giraudoux, P., Baudry, J., Musard, P., Toussaint, M., Truchetet, D., Stahl, P., Poule, M.L., Artois, M., Damange, J.P. & Quéré, J.P. (1992) Land use patterns and types of common vole (Microtus arvalis) population kinetics. Agriculture, Ecosystems and Environment 39, 153–169.CrossRefGoogle Scholar
Deplazes, P. & Eckert, J. (1996) Diagnosis of the Echinococcus multilocularis infection in final hosts. Applied Parasitology 37, 245–252.Google ScholarPubMed
Eckert, J. (2003) Predictive values and quality control of techniques for the diagnosis of Echinococcus multilocularis in definitive hosts. Acta Tropica 85, 157–163.CrossRefGoogle ScholarPubMed
Gilot, B., Doche, B., Deblock, S. & Pétavy, A.F. (1988) Eléments pour la cartographie écologique de l'échinococcose alvéolaire dans le Massif Central: essai de délimitation d'un foyer. Canadian Journal of Zoology 66, 696–702.CrossRefGoogle Scholar
Giraudoux, P., Delattre, P., Takahashi, K., Raoul, F., Quéré, J.P., Craig, P. & Vuitton, D. (2002) Transmission ecology of Echinococcus multilocularis in wildlife: what can be learned from comparative studies and multiscale approaches? pp. 251–262 in Craig, P. & Pawlowski, Z. (Eds) Cestode zoonoses: echinococcosis and cysticercosis. NATO Sciences Series. Amsterdam, IOS Press.Google Scholar
Gottstein, B., Saucy, F., Deplazes, P., Reichen, J., Demierre, G., Busato, A., Zuercher, C. & Pugin, P. (2001) Is high prevalence of Echinococcus multilocularis in wild and domestic animals associated with disease incidence in humans? Emerging Infectious Diseases 7, 408–412.CrossRefGoogle ScholarPubMed
Houin, R., Deniau, M. & Liance, M. (1980) Arvicola terrestris (L.), le premier rongeur trouvé naturellement infesté par Echinococcus multilocularis, Leuckart, 1863, en France. Comptes Rendus de l'Académie des Sciences (Paris), série D 290, 1269–1271.Google Scholar
Liance, M., Janin, V., Bresson-Hadni, S., Vuitton, D.A., Houin, R. & Piarroux, R. (2000) Immunodiagnosis of Echinococcus infection: confirmatory testing and species differentiation by a new commercial western blot. Journal of Clinical Microbiology 38, 3718–3721.CrossRefGoogle ScholarPubMed
Paley, M.R. & Ros, P.R. (1998) Hepatic calcification. Radiology Clinics of North America 36, 391–398.CrossRefGoogle ScholarPubMed
Pétavy, A.-F. & Deblock, S. (1983) Connaissance du foyer auvergnat d'échinococcose alvéolaire. Annales de Parasitologie Humaine et Comparée 58, 439–453.CrossRefGoogle Scholar
Pétavy, A.-F., Deblock, S. & Gilot, B. (1984) Mise en évidence de la larve du Taenia multiloculaire chez 2 campagnols (Microtus arvalis et Clethrionomys glareolus) dans le foyer d'échinococcose alvéolaire du Massif Central (France). Comptes Rendus de l'Académie des Sciences (Paris), série III 299, 735–737.Google Scholar
Pétavy, A.-F., Deblock, S. & Walbaum, S. (1990) The house mouse: a potential intermediate host for Echinococcus multilocularis in France. Transactions of the Royal Society of Tropical Medicine and Hygiene 84, 571–572.CrossRefGoogle ScholarPubMed
Rey, M., Morin, B., Pétavy, A.-F., Cambon, M. & Baril, A. (1977) Premières observations auvergnates d'échinococcose alvéolaire. Nouvelle Presse Medicale 17, 4070–4071.Google Scholar
Viel, J.-F., Giraudoux, P., Abrial, V. & Bresson-Hadni, S. (1999) Water vole (Arvicola terrestris scherman) density as risk factor for human alveolar echinococcosis. American Journal of Tropical Medicine and Hygiene 61, 559–565.CrossRefGoogle ScholarPubMed