Hostname: page-component-5c6d5d7d68-thh2z Total loading time: 0 Render date: 2024-08-22T21:59:28.474Z Has data issue: false hasContentIssue false

Embryogenesis in Litomosoides carinii from pyridoxine deficient cotton rats

Published online by Cambridge University Press:  05 June 2009

M. A. Beg
Affiliation:
University of Salford, Department of Biological Sciences, Salford, M5 4WT, UK
D. M. Storey
Affiliation:
University of Salford, Department of Biological Sciences, Salford, M5 4WT, UK

Abstract

Pyridoxine (vitamin B6) deficiency was induced in cotton rats which were then infected with the filarial parasite Litomosoides carinii. Embryogenesis was assessed microscopically in worms taken from pyridoxine deficient cotton rats and from various categories of control animals. Embryogenesis was retarded in worms from pyridoxine deficient hosts and more abnormal embryos were present in such worms than in those from control animals.

Type
Research Papers
Copyright
Copyright © Cambridge University Press 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Akpom, C. A. (1978) The oogram as a sensitive method of assessing the effect of dietary deficiency on the parasite in experimental schistosomiasis mansoni. Tropical and Geogiaphical Medicine, 30, 219225.Google ScholarPubMed
Axelrod, A. F. & Traketellis, A. C. (1964) Relationship of pyridoxine to immunological phenomena. Vitamins and Hormones, 22, 591607.CrossRefGoogle ScholarPubMed
Beg, M. A. & Storey, D. M. (1992) Litoniosoides carinii infections in pyridoxine deficient rats. Paper read at British Society for Parasitology, Spring meeting, April 6–8, University of York.Google Scholar
Beg, M. A., Ingram, G. A. & Storey, D. M. (1993) Plasma pyridoxal-5-phosphate levels in vitamin B6 deficient cotton rats during infection with Litomosoides carinii. Journal of Nutritional Immunology, 2, (3) (In Press).Google Scholar
Bingham, A. E. (1977) Cotton rat filariasis in vitamin E deficient rats. PhD thesis, University of Salford. UK. 356 pp.Google Scholar
Ellis, D. S., Rogers, R., Bianco, A. E. & Denham, D. A. (1978) Intrauterine development of the microfilariae of Dipetalonema viteae. Journal of Helminthology, 52, 710.CrossRefGoogle ScholarPubMed
Friedheim, E. & Kershaw, W. E. (1963) Filaricidal effect of metal compounds and an alkylating agent. Proceedings of 7th International Congress on Tropical Medicine and Malaria, 2, 135.Google Scholar
Hawking, F. & Worms, M. J. (1967) The effects of antimitotic agents on the filarial worm Litomosoides carinii, in vitro. Journal of Parasitology, 53, 1118.CrossRefGoogle Scholar
Jayapragasam, M., Bagai, R. C. & Sybrahmanyam, D. (1977) The effect of malnutrition and filarial infection in albino rats. Indian Journal of Medical Research, 65, 346352.Google Scholar
Kershaw, W. E. & Storey, D. M. (1976) Host parasite relations in cotton rat filariasis, I. The quantittive transmission and subsequent development of Litomosoides carinii infections in cotton rats and other laboratory animals. Annals of Tropical Medicine and Parasitology, 70, 303312.Google Scholar
Mcfadzean, J. A. & Smiles, J. (1956) Studies of Litomosoides carinii by phase contrast microscopy: the development of the larvae. Journal of Helminthology, 30, 2532.CrossRefGoogle ScholarPubMed
Mclaren, D. S. (1974) The great protein fiasco. Lancet, 2,9396.CrossRefGoogle ScholarPubMed
Mossinger, J. & Wenk, P. (1986) Fecundity of Litomosoides carinii (Nematoda: Filarioidea) in vivo and in vitro. Zeitschrift für Parasitenkunde. 72, 121–13 I.CrossRefGoogle ScholarPubMed
Prasad, R., Rao, Y. V. B. G., Sindhu, R. K. & Subrahmanyam, D. (1980a) The effect of pyridoxine deficiency on the infection of albino rats with Litomosoides carinii. Transactions of the Royal Society of Tropical Medicine and Hygiene, 74, 459462.CrossRefGoogle ScholarPubMed
Prasad, R., Rao, Y. V. B. G., Mehta, K. & Subrahmanyam, D. (1980b) The effect of thiamine deficiency in filarial infection in albino rats with Litomosoides carinii. International Journal for Parasitology, 10, 9396.CrossRefGoogle ScholarPubMed
Rogers, R., Ellis, D. S. & Denham, D. S. (1976) Studies with Brugia pahangi. 14. Intrauterine development of the microfilaria and a comparison with other filarial species. Journal of Helnonthology, 50, 251257.CrossRefGoogle Scholar
Shamran, S. H. (1988) The effect of vitamin A deficiency on the host parasite relationships in jirds, Meriones unguiculatus infected with Dipetalonema viteae. M.Sc. Thesis, University of Salford. 122pp.Google Scholar
Storey, D. M. (1981) Parasite infection and host nutrition. Proceedings of Third European Multicolloquium of Parasitology. Parasitology, 82, Part 4, 3536.Google Scholar
Storey, D. M. (1982a) The host parasite relations in normal and protein malnourished cotton rats infected with Litomosoides carinii (Nematoda: Filarioidea). Parasitology, 85, 543558.CrossRefGoogle Scholar
Storey, D. M. (1982b) Vitamin A deficiency and the development of Litomosoides caninii (Nematoda: Filarioidea) in cotton rats. Zeitschrift für Parasitenkunde, 67, 309315.CrossRefGoogle ScholarPubMed
Sturchler, D., Hanck, A., Weiser, H., Manz, U. & Weiss, N. (1985) Retinol deficiency and Dipetalonema viteae infection in the hamster. Journal of Helminthology, 59, 201210.CrossRefGoogle ScholarPubMed
Taylor, A. E. R. & Terry, R. J. (1960) The effect of antifilarial drugs on the embryonic development of Litomosoides carinii, filarial parasite of the cotton rat. Transactions of the Royal Society of Tropical Medicine and Hygiene, 54, 3336.Google Scholar
Terry, A., Terry, R. J. & Worms, M. J. (1961) Dipetalonema witei, filarial parasite of the jird, Meriones unguiculatus II. The reproductive systenm, gametogenesis and development of the microfilaria. Journal of Parasitology, 47, 703711.CrossRefGoogle Scholar
Vankan, D. M. & Copeman, D. B. (1988) Reproduction in female Onchocerca gibsoni. Tropical Medicine and Parasitology, 39, 469471.Google Scholar
Waterlow, J. C. & Payne, R. R. (1975) The protein gap. Nature, 258, 113117.CrossRefGoogle ScholarPubMed
Wenk, P. & Neef, U. (1969) Die regulation der parasitaemie bei filarien (Litomosoides carinii). Zoologischer Anzeiger (Supplement) 33, 9295.Google Scholar