Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-25T01:36:17.819Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of Trichinella spiralis on the rate of clearance of 51 Cr-labelled sheep red blood cells and 125I-polyvinyl pyrrolidone from the bloodstream of mice

Published online by Cambridge University Press:  05 June 2009

Nagwa A. N. Aboul-Atta ,
M. W. Steward  and
D. A. Denham
Nagwa A. N. Aboul-Atta
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT
M. W. Steward
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT
D. A. Denham
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT
Get access Rights & Permissions [Opens in a new window]

Abstract

Mice infected for one to eight weeks with Trichinella spiralis cleared either 51Cr-labelled sheep red blood cells (SRBC) or I-polyvinyl pyrrolidone (PVP) given intravenously. PVP was cleared more rapidly from the blood of mice infected for one week than from uninfected mice with older infections which behaved in a similar manner to the controls. SRBC were consistently cleared faster from the blood of mice infected for one week than from normal mice. If the infections were older than this a more rapid clearance was also demonstrated as long as the infections were reasonably heavy.

Type
Research Article
Information
Journal of Helminthology , Volume 55 , Issue 4 , December 1981 , pp. 287 - 293
Copyright
Copyright © Cambridge University Press 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Cypess, R. H.Lubiniecki, A. S. & Swidwa, D. M. (1976) Decreased susceptibility to Listeria monocytogenes in mice after infection with Trichinella spiralis. Infection and Immunity, 9,477–479.CrossRefGoogle Scholar
Denham, D. A. (1968) Immunity to Trichinella Spiralis III. The longevity of the intestinal phase of the infection in mice. Journal of Helminthology, 42, 257–268.CrossRefGoogle Scholar
Faubert, G. M. (1976) Depression of the plaque-forming cells to sheep red blood cells by the new-born larvae of Trichinella spiralis. Immunology, 30, 485–489.Google ScholarPubMed
Ljungström, I. & Huldt, G. (1977) Effect of experimental trichinosis on unrelated humoral and cell mediated immunity. Acta Pathologica Microbiologica Scandinavia Section C, 85, 131–141.CrossRefGoogle ScholarPubMed
Lubiniecki, A. S., Cypess, R.H. & Lucas, J. P. (1974) Immune response to and distribution of sheep erythrocytes in Trichinella spiralis infected mice. Tropenmedizin und Parasitologie, 25, 345–349.Google ScholarPubMed
Meerovitch, E. & Ackerman, S.J. (1974) Trypanosomiasis in rats with trichinosis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 68, 417.CrossRefGoogle ScholarPubMed
Meerovitch, E. & Bomford, R. (1977) Macrophage potentiation by Trichinella spiralis. Annals of Tropical Medicine and Parasitology, 71, 245–246.CrossRefGoogle ScholarPubMed
Morgan, A.G. & Soothill, J. F. (1975) Measurement of the clearance function of macrophages with I-labelled polyvinyl pyrrolidone. Clinical and Experimental Immunology, 20, 489–498.Google Scholar
Svet-Moldavsky, G.J., Shaghijan, G.S., Chernyakiiovskaya, I.Y., Mkheldye, D.M., Litovsciienko, T. A., Ozeretskovskaya, N. N. & Kadaghidye, Z. G. (1970) Inhibition of skin allograft rejection in Trichinella infected mice. Transplantation, 9, 69–71.CrossRefGoogle ScholarPubMed
Weiner, E. & Bandieri, A. (1974) Differences in antigen handling by peritoneal macrophages from the Biozzi high and low respondcr strains of mice. European Journal of Immunology, 4, 457–463.CrossRefGoogle Scholar
Wing, E. J. & Remington, J. S. (1977) Studies on the regulation of lymphocyte reactivity by normal and activated macrophages. Cellular Immunology, 30, 108–121.CrossRefGoogle ScholarPubMed
Wing, E.J. & Remington, J.S. (1978) Role for activated macrophages in resistance against Trichinella spiralis. Infection and Immunity, 21, 398–404.CrossRefGoogle ScholarPubMed
Wing, E. J., Krahenbuhl, J.L.Remington, J.S. (1979), Studies of macrophage function during Trichinella spiralis infection in mice. Immunology, 36, 479–485.Google ScholarPubMed