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Effect of papaya latex against Ascaris suum in naturally infected pigs

Published online by Cambridge University Press:  05 June 2009

F. Satrija ,
P. Nansen ,
H. Bjørn ,
S. Murtini  and
S. He
F. Satrija
Affiliation:
Danish Centre for Experimental Parasitology, Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark Laboratory of Helminthology, Department of Parasitology and Pathology, Faculty of Veterinary Medicine, Bogor Agricultural University, Jl. Taman Kencana No. 3, Bogor 16151, Indonesia
P. Nansen*
Affiliation:
Danish Centre for Experimental Parasitology, Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark
H. Bjørn
Affiliation:
Danish Centre for Experimental Parasitology, Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark
S. Murtini
Affiliation:
Danish Centre for Experimental Parasitology, Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark Laboratory of Helminthology, Department of Parasitology and Pathology, Faculty of Veterinary Medicine, Bogor Agricultural University, Jl. Taman Kencana No. 3, Bogor 16151, Indonesia
S. He
Affiliation:
Laboratory of Helminthology, Department of Parasitology and Pathology, Faculty of Veterinary Medicine, Bogor Agricultural University, Jl. Taman Kencana No. 3, Bogor 16151, Indonesia
*
*Author for correspondence.
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Abstract

An experiment was carried out to investigate the anthelmintic activity of papaya latex (Carica papaya) against natural infection of Ascaris suum in pigs. Sixteen naturally infected pigs were, on the basis of faecal egg counts and body weight, allocated into four groups, each of four pigs. Three groups (groups B, C, and D) were given papaya latex per os at dose levels of 2, 4, and 8 g of papaya latex per kg body weight, respectively. The fourth group (group A) served as a non-treated control. Results of post mortem counts on day 7 post treatment revealed worm count reductions of 39.5, 80.1 and 100% in groups B, C, and D, respectively. Some of the pigs receiving the highest dose of the latex showed mild diarrhoea on the day following treatment. Otherwise, no clinical or pathological changes were observed in the treated animals. The possible future use of this traditional herbal medicine for livestock and humans is discussed.

Type
Research Papers
Information
Journal of Helminthology , Volume 68 , Issue 4 , December 1994 , pp. 343 - 346
Copyright
Copyright © Cambridge University Press 1994

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References

Dharma, A.P. (1985) Tanaman obat tradisional Indonesia. 291 pp. Jakarta, PN: Balai Pustaka.Google Scholar
Hawley, J.H. & Peanasky, R.J. (1992) Ascaris suum: Are trypsin inhibitors involved in species specificity of ascarid nematodes? Experimental Parasitology 75, 112–118.CrossRefGoogle ScholarPubMed
Martenz, M.R., Geise, G.L., Hogan, B.J. & Peanasky, R.J. (1985) Ascaris suum: Localization by immunochemical and fluorescent probes of host protease and parasite proteinase inhibitors in cross sections. Experimental Parasitology 60, 139–149.Google Scholar
Mursof, E.P. & He, S. (1991) A potential role of papaya latex as an anthelmintic against patent Ascaridia galli infection in chicken. Hemera Zoa 74, 11–20.Google Scholar
Peanasky, R.J. & Abu-Erreish, G.M. (1971) Inhibitors from Ascaris lumbricoides: Interaction with the host's digestive system. Proceeding of the International Research Conference on Proteinase Inhibitors, pp. 281–293.Google Scholar
Perry, L.M. (1980) Medical plants of East and Southeast Asia. 620 pp. London, The MIT Press.Google Scholar
Purwati, E. & He, S. (1991a) Pengaruh getah pepaya (Carica papaya) terhadap infektivitas telur Ascaridia galli pada ayam. Hemera Zoa 74, 1–5.Google Scholar
Purwati, E. & He, S. (1991b) Pengaruh getah pepaya (Carica papaya) terhadap Ascaridia galli dewasa in vitro. Hemera Zoa 74, 6–10.Google Scholar
Reed, G. & Underkofler, L.A. (1966) Enzymes in food processing. London, Academic Press.Google Scholar
Roepstorff, A. & Nansen, P. (1994) Epidemiology and control of helminth infections in pigs under intensive and non-intensive production systems. Veterinary Parasitology (in press).CrossRefGoogle ScholarPubMed
SAS Institute Inc. (1985) Users guide: statistics, pp. 891–996. Cary, N.C., USA.Google Scholar
Winarno, F.G. (1983) Enzym pangan 115 pp. Jakarta, PT Gramedia.Google Scholar