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Effect of mode of infection on the development and chemotherapeutic response of Hymenolepis nana in rats

Published online by Cambridge University Press:  18 November 2009

Suman Gupta
Affiliation:
Division of Parasitology, Central Drug Research Institute, Lucknow-226001, India
J. C. Katiyar
Affiliation:
Division of Parasitology, Central Drug Research Institute, Lucknow-226001, India
A. B. Sen
Affiliation:
Division of Parasitology, Central Drug Research Institute, Lucknow-226001, India

Abstract

The susceptibility of rats to Hymenolepis nana (Cestoda) and the chemotherapeutic response of anti-cestode drugs was studied during egg-induced and cysticercoid-induced infections. In cysticercoid-induced infection, the percentage of infected animals and the number of mature worms were significantly more than in egg-induced infection. The former mode of transmission required more drug to clear the parasites. These differences have been discussed on the basis of immunity engendered in the definitive host by the developing larvae.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1981

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