Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-28T15:10:29.531Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of controlled release copper sulphate and tributyltin fluoride on the mortality and infectivity of Schistosoma mansoni cercariae

Published online by Cambridge University Press:  18 November 2009

Vithoon Viyanant ,
Sanam Thirachantra  and
Santasiri Sornmani
Vithoon Viyanant
Affiliation:
Department of Biology, Faculty of Science, Mahidol University, Bangkok 4, Thailand
Sanam Thirachantra
Affiliation:
Department of Biology, Faculty of Science, Mahidol University, Bangkok 4, Thailand
Santasiri Sornmani
Affiliation:
Department of Biology, Faculty of Science, Mahidol University, Bangkok 4, Thailand
Get access Rights & Permissions [Opens in a new window]

Abstract

Mortality and infectivity or Schistosoma mansoni cercariae were tested against various concentrations of controlled release copper sulphate (EC-8) and tributyltin fluoride (CBL-9B). The results indicate that survival of cercariae varied with concentrations of molluscicide and times of exposures. Statistical analysis reveals that LC50 and LC90 for EC-8 were 1·8mg/1/hour and 1·82 mg/1/hour while LC50 and LC90 for CBL-9B were 16·8 μg/1/hour and 21·7 μg/1/hour respectively. Sublethal concentration of both molluscicides reduced cercarial infectivity considerably. The doses of 0·25 to 0·5 mg/1/hour for EC-8 and 2·0 to 6·0 μg/1/hour for CBL-9B were found to be sufficient to inhabit cercarial penetration of the host skin.

Type
Research Papers
Information
Journal of Helminthology , Volume 56 , Issue 2 , June 1982 , pp. 85 - 92
Copyright
Copyright © Cambridge University Press 1982

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Appleton, C. C. & Stiles, G. (1976) A preliminary field trial with the slow release molluscicide “INCRACIDE E-51”, Proceedings of Controlled Release Pesticide Symposium, University of Akron, Oh, USA.Google Scholar
Arfaa, F. (1976) Field trial with slow release molluscicide, Proceedings of Controlled Release Pesticide Symposium, University of Akron, Oh., USA.Google Scholar
Campdell, W. C. & Cuckler, A. C. (1961) The prophylactic effect of topically applied cedarwood oil on infection with Schistosoma monsoni in mice. American Journal of Tropical Medicine and Hygiene, 10, 712–715.CrossRefGoogle Scholar
Cardarelli, N. F. (1974) Cercariacidal potency of slow release molluscicides. Proceedings of Controlled Release Pesticide Symposium, Report No. 39, University of Akron, Akron, Oh., USA.Google Scholar
Cardarelli, N. F. (1977a) Controlled release molluscicides. Environmental Management Laboratory Monograph. University of Akron, Akron, Oh., USA.Google Scholar
Cardarelli, N. F. (1977b) Laboratory and field evaluation of controlled release molluscicidcs and schistolarvicidcs. Progress Report VII, The Edna McConncll Clark Foundation.Google Scholar
Christie, J. D., Prentice, M. A., Upatham, E. S. & Barnish, G. (1978) Laboratory and field trials of a slow-release copper molluscicide in St. Lucia. American Journal of Tropical Medicine and Hygiene, 27, 616–622.CrossRefGoogle ScholarPubMed
Finney, D. J. (1971) Probit analysis. Cambridge University Press, London.Google Scholar
Ghandour, A. M. & Webbe, G. (1975) The effect of sublethal concentrations of the molluscicide niclosamide on the infectivity of Schistosoma monsoni cercariae. Journal of Helminthology, 49, 245–250.CrossRefGoogle Scholar
Healy, M. J. R. (1952) A table of Abbott's correction for natural mortality. Annals of Applied Biology, 39, 211–212.CrossRefGoogle Scholar
Hira, P. R. & Webbe, G. (1972) The effect of sublethal concentrations of the molluscicide triphenyl lead acetate in Biomphalaria glabrata (Say) and on the development of Schistosoma monsoni in the snail. Journal of Helminthology, 46, 11–26.CrossRefGoogle Scholar
Lewert, R. M., Hopkins, D. R. & Mandlowitz, S. (1966) The role of calcium and magnesium in invasiveness of schistosome cercariae. American Journal of Tropical Medicine and Hygiene, 15, 314–323.CrossRefGoogle ScholarPubMed
Malek, E. A. (1962) Bilharziasis control in pump schemes near Khartoum, Sudan, and an evaluation of the efficience of chemical and mechanical barriers. Bulletin of The World Health Organization, 27, 41–58.Google Scholar
Malek, E. A. (1974) A note on the uses of copper compounds as molluscicides. In “Molluscicides in schistosomiasis control” Cheng, T. C. (Editor) pp. 171–175. Academic Press, New York.Google Scholar
Massoud, J. & Webbe, G. (1969) The effect of sublethal doses of the molluscicide (N-trityl-morpholine) on the development of Schistosoma monsoni in Biomphalaria glabrata (Say). Journal of Helminthology, 43, 99–110.CrossRefGoogle Scholar
Mecham, J. A. & Holliman, R. B. (1975) Toxicity of zine to Schistosoma monsoni cercariae in a chemically defined water medium. Hydrobiologia, 46, 391–404.CrossRefGoogle Scholar
Ritchie, L. S. & Malek, E. A. (1969) Molluscicides: Status of their evaluation formulation and methods of application. WHO Rep. Series, PD/MOL/69.1.Google Scholar
Ritchie, L. S., Lorez, V. A. & Cora, J. M. (1974) Prolonged applications of an organotin against Biomphalaria glabrata and schistosomiasis control. In: “Molluscicides in schistosomiasis control” Cheng, T. C. (Editor), pp. 77–88. Academic Press, New York.Google Scholar
Smithers, S. R. & Terry, R. J. (1965) The infection of laboratory hosts with cercariae of Schistosoma monsoni and the recovery of adult worms. Parasitology, 55, 695–700.CrossRefGoogle Scholar
Viyanant, V., Thirachantra, S. & Sornmani, S. (1977) A simple restraining case for infecting mouse to schistosome cercariae. Southeast Asian Journal of Tropical Medicine and Public Health, 8, 415–416.Google Scholar