Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-25T08:21:09.889Z Has data issue: false hasContentIssue false
  • English
  • Français

Cross protection against Taenia taeniaeformis in rats vaccinated with non-viable oncospheres of Asian Taenia or T. saginata

Published online by Cambridge University Press:  05 June 2009

A. Ito ,
P.C. Fan ,
W.C. Chung  and
M. Suzuki
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu 500, Japan
P.C. Fan
Affiliation:
Department of Parasitology, National Yang-Ming Medical College, Taipei, Taiwan, Republic of China
W.C. Chung
Affiliation:
Department of Parasitology, Taipei Medical College, Taipei, Taiwan, Republic of China
M. Suzuki
Affiliation:
Department of Parasitology, Gumma University School of Medicine, Maebashi, Japan
Get access Rights & Permissions [Opens in a new window]

Abstract

It was determined to examine whether rats injected with non-viable oncospheres of Asian Taenia or Taenia saginata became resistant to challenge infection with eggs of Taenia taeniaeformis, since (a) metacestodes of Asian Taenia and T. taeniaeformis develop in the liver of pigs and rats, respectively, and (b) Asian Taenia and T. saginata have human origins. Rats injected intravenously or subcutaneously with complete Freund's adjuvant with non-viable oncospheres of Asian Taenia showed statistically significant resistance to challenge infection with eggs of T. taeniaeformis, whereas those injected with non-viable oncospheres of T. saginata did not show any resistance.

Type
Research Note
Information
Journal of Helminthology , Volume 68 , Issue 1 , March 1994 , pp. 83 - 85
Copyright
Copyright © Cambridge University Press 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chan, C.H., Fan, P.C., Chung, W.C., Chen, Y.A., Wu, C.C., Hsu, M.C. & Chao, D. (1987) Studies on taeniasis in Taiwan. I. Prevalence of taeniasis among aborigines in Wulai District, Taipei Country, Northern Taiwan. Proceedings of the 1st Sino-American Symposium on Biotechnology and Parasitic Diseases, 1, 65–77.Google Scholar
Chung, W.C., Fan, P.C., Chan, C.H., Hsu, M.C. & Yu, Y.I. (1988) Studies on taeniasis in Taiwan. VII. Prevalence of taeniasis among Atayal aborigines in Tatung District, Ilan Country, Northeast Taiwan. Chinese Journal of Parasitology, 1, 152–166.Google Scholar
Fan, P.C. (1988). Taiwan Taenia and taeniasis. Parasitology Today 4, 86–88.CrossRefGoogle ScholarPubMed
Fan, P.C., Chung, W.C., Lin, C.Y., Soh, C.T., Lee, K.T., Kosman, M.L., Kosin, E., Depari, A.A. & Napitupulu, T. (1988) Studies on taeniasis in Taiwan. VI. Is Taenia saginata from Taiwan, Korea, and Indonesia a new species? Chinese Journal of Parasitology 1, 56–70.Google Scholar
Harrison, G.B.L., Heath, D.D., Dempster, R.P., Lawrence, S.B., Lightowlers, M.W. & Rickard, M.D. (1993) Identification of host-protective antigens of Taenia ovis oncospheres. International Journal for Parasitology 23, 41–50.CrossRefGoogle ScholarPubMed
Ito, A. (1992) Cysticercosis in Asian-Pacific Regions. Parasitology Today 8, 181–182.CrossRefGoogle ScholarPubMed
Ito, A. & Hashimoto, A. (1993) Vaccination with hatched but non-activated, non-viable oncospheres of Taenia taeniaeformis in rats. Journal of Helminthology 67, 165–168.CrossRefGoogle ScholarPubMed
Ito, A., Bøgh, H., Lightowlers, M.W. & Rickard, M.D. (1988) Cross-resistance between Taenia taeniaeformis and Hymenolepis nana infections in C3H/He mice. International Journal for Parasitology 18, 691–694.CrossRefGoogle ScholarPubMed
Ito, A., Onitake, K., Sasaki, J. & Takami, T. (1991a) Hymenolepis nana: Immunity against oncosphere challenge in mice previously given viable or non-viable oncospheres of H. nana, H. diminuta, H. microstoma and Taenia taeniaeformis. International Journal for Parasitology 21, 241–245.CrossRefGoogle ScholarPubMed
Ito, A., Bøgh, H., Lightowlers, M.W., Mitchell, G.F., Takami, T., Kamiya, M., Onitake, K. & Rickard, M.D. (1991b) Vaccination against Taenia taeniaeformis infection in rats using a recombinant protein and preliminary analysis of the induced antibody response. Molecular and Biochemical Parasitology 44, 43–52.CrossRefGoogle ScholarPubMed
Johnson, K.S., Harrison, G.B.L., Lightowlers, M.W., O'Hoy, K.L., Cougle, W.G., Dempster, R.P., Lawrence, S.B., Vinton, J.G., Heath, D.D. & Rickard, M.D. (1989) High level protection against a helminth parasite induced by a defined recombinant antigen. Nature 338, 585–587.CrossRefGoogle Scholar
Lightowlers, M.W., Mitchell, G.F., Bowtell, D.D.L., Anders, R.F. & Rickard, M.D. (1984) Immunisation against Taenia taeniaeformis in mice: studies on the characterisation of antigens from oncospheres. International Journal for Parasitology 14, 321–333.CrossRefGoogle ScholarPubMed
Lightowlers, M.W., Mitchell, G.F. & Rickard, M.D. (1993) Cestodes. pp. 438–472in Warren, K.S. (Ed.) Immunology and molecular biology of parasitic infections. Oxford, Blackwell.Google Scholar
Onitake, K., Sasaki, J., Andreassen, J. & Ito, A. (1989) Hymenolepis microstoma oncospheres invade the intestinal tissue of the definitive host. Journal of Helminthology 69, 170–172.Google Scholar
Thompson, R.C.A., Penhale, W.J., White, D.A. & Pass, D.A. (1982) BCG-induced inhibition and destruction of Taenia taeniaeformis in mice. Parasite Immunology 4, 93–99.CrossRefGoogle ScholarPubMed
Zarlenga, D.S., McManus, D.P., Fan, P.C. & Cross, J.H. (1991) Characterization and detection of a newly described Asian taeniid using cloned ribosomal DNA fragments and sequence amplification by the polymerase chain reaction. Experimental Parasitology 72, 174–183.CrossRefGoogle ScholarPubMed