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Comparative study of assays detecting circulating immune complexes and specific antibodies in patients infected with Toxocara canis

Published online by Cambridge University Press:  05 June 2009

C. Aguila ,
C. Cuéllar ,
S. Fenoy  and
J. L. Guillén
C. Aguila
Affiliation:
Departamento de Biologia Molecular, Inst. Llorente-Fides, 28035 Madrid, Spain
C. Cuéllar
Affiliation:
Departamento de Parasitología, Facultad de Farmacia, U.C.M., 28040 Madrid, Spain
S. Fenoy
Affiliation:
Departamento de Parasitología, Facultad de Farmacia, U.C.M., 28040 Madrid, Spain
J. L. Guillén
Affiliation:
Departamento de Parasitología, Facultad de Farmacia, U.C.M., 28040 Madrid, Spain
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Abstract

A sandwich ELISA method using previously described E/S antigen-specific monoclonal antibodies has been developed to detect circulating immune complexes in patients infected with Toxocara canis. This technique could be used for the study of the dynamics of the parasite-host relationship, as we believe the detection of immune complexes and/or soluble antigen to be an improvement over detection of antibodies only. In this parasitosis, antibodies may be present in residual levels for prolonged periods after active infection.

Keywords

ELISAToxocara caniscirculating immune complexesmanimmunodiagnosis.
Type
Research Papers
Information
Journal of Helminthology , Volume 61 , Issue 3 , September 1987 , pp. 196 - 202
Copyright
Copyright © Cambridge University Press 1987

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