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The Bilharzia Complement Fixation Reaction in Goats infected with Schistosoma mattheei and Schistosoma bovis

Published online by Cambridge University Press:  05 June 2009

N. Hamilton Fairley
N. Hamilton Fairley
Affiliation:
(Lecturer in Applied Pathology and Clinical Medicine, London School of Hygiene and Tropical Medicine.)
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Extract

1. The sera of 18 goats were investigated for the bilharzia complement fixation reaction, using as antigen alcoholic extract of the livers of snails (Planorbis exustus) infected with cercariae of S. spindale.

2. The sera of 5 out of 7 goats harbouring S. mattheei, and of 4 out of 4 goats exposed to alimentary infection with S. bovis yielded positive results, the range of complement fixation varying from 5 to 20 M.H.D.'s.

3. The sera of non-infected goats and of 3 goats exposed to infection with cercariae of S. mansoni from which these animals appear naturally immune, yielded negative reactions.

4. The complement fixation reaction with cercarial antigen (S. spindale) has now been applied to infestation with 3 human and 4 cattle schistosomes, and its group applicability to mammalian schistosomiasis may be regarded as proven.

Type
Research Papers
Information
Journal of Helminthology , Volume 11 , Issue 4 , October 1933 , pp. 181 - 186
Copyright
Copyright © Cambridge University Press 1933

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References

Cawston, F. G., 1921.—“Bilharzia-infested snails and their employment as antigen.” Lancet, xcix, pp. 250. (W.L. 11995.)CrossRefGoogle Scholar
Fairley, N. Hamilton, 1919.—“The discovery of a specific complement fixation test for Bilharziasis and its practical application to clinical medicine”. R.A.M.C. Jl., xxxii (6), pp. 449–460, 2 tables, 11 refs. (W.L. 11035.)Google Scholar
Fairley, N. Hamilton, 1923.—Trans. Indian Sc. Congress. Society of Bengal Publications.Google Scholar
Fairley, N. Hamilton. 1925.—“Complement fixation with Bilharzia. Part I. The lipoidal nature of cercarial antigen as used in the complement fixation test for mammalian Bilharziosis”. J. Path. Bact., xxviii (4), pp. 591–607, 7 tables, 30 refs. (W.L. 11431.)CrossRefGoogle Scholar
Fairley, N. Hamilton. 1926.—“The serological diagnosis of Schistosomum spindalis”. Arch. Schiffs.- u. Tropenhyg., xxx (9), pp. 372–382, 7 refs. (W.L. 1804.)Google Scholar
Fairley, N. Hamilton. 1927a.—“The early spontaneous cure of Bilharziosis (S. spindalis) in monkeys, (Macacus sinicus) and its bearing on species immunity”. Ind. J. Med. Res., xiv (3), pp. 685–700, 3 pls., 17 refs. (W.L. 9940.)Google Scholar
Fairley, N. Hamilton. 1927b.—“Complement fixation with Bilharzia. Part II. The production of specific antibody by intravenous injections of protein-free alcohol-soluble cercarial extracts”. J. Path. Bact., xxx (1), pp. 97–112, 6 figs., 41 refs. (W.L. 11431.)CrossRefGoogle Scholar
Fairley, N. Hamilton., 1930.—“Studies in Schistosoma spindale. Part VI. The complement fixation reaction with cercarial antigen.—A study in experimental serology.” Ind. Med. Res. Mem., No. 17, pp. 73–143 (Appendix pp. 145–180), 18 graphs, 22 protocol, 24 refs.Google Scholar
LeBas, G. Z. L., 1922.—“Of the nature of the antigen in the complement-fixation test for Bilharziosis”. J. Trop. Med., xxv (3), pp. 49–55, 5 tables, 30 refs. (W.L. 11587.)Google Scholar
Murray, W. A., 1920.—“Note on a specific complement-fixation test for Bilharziasis”. S. Afr. Med. Rec., xviii (9), pp. 168–169. (W.L. 20360.)Google Scholar
Tanabe, B., 1923.—“Complement-fixation test of Schistosomatium pathlocopticum and its group reaction with Schistosoma japonicum.” J. Parasit., ix (4), pp. 230–233, 2 tables, 4 refs. (W.L. 11428.)CrossRefGoogle Scholar