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Anomalous Results from an Experimental Infection of Man with Brugia malayi (Brug, 1927)

Published online by Cambridge University Press:  05 June 2009

J. J. C. Buckley
Affiliation:
From the London School of Hygiene and Tropical Medicine and the Institute for Medical Research, Kuala Lumpur, Federation of Malaya
R. H. Wharton
Affiliation:
From the London School of Hygiene and Tropical Medicine and the Institute for Medical Research, Kuala Lumpur, Federation of Malaya

Extract

A volunteer who had been previously exposed to infection with filarial infections from naturally infected animals, i.e., Brugia malayi from Macaca irus and B. pahangi from a domestic cat, was exposed to infection with B. malayi from man. He developed signs and symptoms of tropical pulmonary eosinophilia and transitory swellings of the lower limbs, possibly of filarial origin. Up to the time of treatment with Banocide no microfilariae were found in his blood.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1961

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References

Buckley, J. J. C., 1958.—“Tropical pulmonary eosinophilia in relation to filarial infections (Wuchereria spp.) of animals.Trans. R. Soc. trop. Med. Hyg., 52, 335336. (W.L. 21671.)CrossRefGoogle ScholarPubMed
Buckley, J. J. C., 1958.—“Occult filarial infections of animal origin as a cause of tropical pulmonary eosinophilia.E. Afr. med. J., 35, 493500. (W.L. 7522c.)Google Scholar
Danaraj, T. J., 1956.—“The treatment of eosinophilic lung (tropical eosinophilia) with hetrazan (a preliminary report).Proc. Alumni Ass. Malaya, 9, 172187. (W.L. 16598a.)Google Scholar
Danaraj, T. J., da Silva, L. S., and Schacher, J. F., 1957.—“The filarial complement-fixation test in eosinophilic lung (tropical eosinophilia)—a preliminary report.Ibidem, 10, 109116.Google Scholar
Edeson, J. F. B. and Wharton, R. H., 1958.—“The experimental transmission of Wuchereria malayi from man to various animals.Trans. R. Soc. trop. Med. Hyg., 52. 2545. (W.L. 21671.)CrossRefGoogle Scholar
Edeson, J. F. B., Wilson, R., Wharton, R. H. and Laing, A. B. G., 1960.—“Experimental transmission of Brugia malayi and B. pahangi to man.Ibidem, 54, 229234.Google Scholar
Webb, J. K. G., Job, C. K. and Gault, E. W., 1960.—“Tropical Eosinophilia. Demonstration of Microfilariae in Lung, Liver and Lymph-Nodes.” Lancet, 1, No. 7129, 835842. (W.L. 11996.)CrossRefGoogle Scholar
Wilson, T., Edeson, J. F. B., Wharton, R. H., Reid, J. A., Turner, L. H. and Laing, A. B. G., 1958.—“The occurrence of two forms of Wuchereria malayi in man.” (Correspondence). Trans. R. Soc. trop. Med. Hyg., 52, 480. (W.L. 21671.)CrossRefGoogle Scholar