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Trichinella spiralis: specificity of ES antigens from pre-encysted larvae

Published online by Cambridge University Press:  05 June 2009

R. C. Ko  and
T. P. Wong
R. C. Ko
Affiliation:
Department of Zoology, University of Hong Kong, Hong Kong
T. P. Wong
Affiliation:
Department of Zoology, University of Hong Kong, Hong Kong
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Abstract

Excretory/secretory (ES) antigens were obtained by culturing pre-encysted Trichinella spiralis larvae which were recovered from muscles of experimentally infected mice 14–15 days postinfection. Analyses of these antigens (PEL ES) with immunoblotting, SDS-PAGE and Triple Antibody ELISA showed that they yielded a low sensitivity and specificity when tested antisera against the common nematodes of Chinese pigs. As compared to ES antigens from encysted larvae. PEL ES also contained more low molecular mass proteins.

Keywords

Trichinella spiralispre-encysted larvaeES antigensspicificityNematodaimmunology
Type
Research Article
Information
Journal of Helminthology , Volume 66 , Issue 1 , March 1992 , pp. 38 - 44
Copyright
Copyright © Cambridge University Press 1992

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References

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