Hostname: page-component-745bb68f8f-s22k5 Total loading time: 0 Render date: 2025-01-23T04:53:39.076Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies on the Malayan forest rat filaria, Breinlia booliati: Periodicity and microfilaraemic patterns during the course of infection*

Published online by Cambridge University Press:  05 June 2009

Eu-Hian yap ,
Beng-Chuan Ho ,
Mulkit Singh ,
Kim-Lian Kang  and
Boo-Liat Lim
Eu-Hian yap
Affiliation:
Department of Parasotology, Faculty of Medicine, University of Singapore, Sepoy Lines., Singapore 3, Republic of Singapore
Beng-Chuan Ho
Affiliation:
Department of Parasotology, Faculty of Medicine, University of Singapore, Sepoy Lines., Singapore 3, Republic of Singapore
Mulkit Singh
Affiliation:
Department of Parasotology, Faculty of Medicine, University of Singapore, Sepoy Lines., Singapore 3, Republic of Singapore
Kim-Lian Kang
Affiliation:
Department of Parasotology, Faculty of Medicine, University of Singapore, Sepoy Lines., Singapore 3, Republic of Singapore
Boo-Liat Lim
Affiliation:
Institute for Medical Research, Kuala Lumper, Malaysia
Get access Rights & Permissions [Opens in a new window]

Abstract

Breinlia booliati exhibited nocturnal subperiodicity in its natural host, Rattus sabanus in contrast to experimentally infected laboratory-reared albino rats which showed irregular fluctuations of microfilariae throughout the 24 hour cycle. All the infected albino rats showed a prepatent period between 11–14 weeks postinoculation. Three patterns of microfilaraemia were discerned during the course of infection. 38/49 rats displayed a single peak, 4/49 displayed 2 peaks about 12–15 weeks apart and 7/49 showed a sustained high plateau-like pattern of microfilaraemia.

Cortisone had no effect on microfilarial levels when administered to rats near postpatcncy and some at postpatency.

Type
Research papers
Information
Journal of Helminthology , Volume 49 , Issue 4 , December 1975 , pp. 263 - 269
Copyright
Copyright © Cambridge University Press 1975

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCE

Ash, L.R. (1973) Chronic Brugia pahangi and Brugia malayi infections in Meriones unguiculatus. Journal of Parasitology, 59, 442–447.Google Scholar
Ash, L.R. and Riley, J.M. (1970) Development of Brugia pahangi in the jird, Meriones unguiculatus, with notes on infections in other rodents. Journal of Parasitology, 56, 962–968.Google Scholar
Bagai, R.C. and Subrahmanyam, D. (1968) Studies on the host-parasite relation in albino rats infected with Litomosoidcs carinii. American Journal of Tropical Medicine and Hygiene, 17, 833–839.Google Scholar
Bagai, R.C. and Subrahmanyam, D. (1970) Nature of acquired resistance to filarial infection in albino rats. Nature, 228, 682–683.CrossRefGoogle ScholarPubMed
Beaver, P.C., Orihel, T.C. and Johnson, M.H. (1974) Dipetalonema viteae in the experimentally infected jird, Meriones unguiculatus. II. Microfilaraemia in relation to worm burden. Journal of Parasitology, 60, 310–315.Google Scholar
Bertram, D.S. (1966) Dynamics of parasitic equilibrium in cotton rat filariasis. Advances in Parasitology, 4, 255–319.CrossRefGoogle ScholarPubMed
Denham, D.A., Ponnudurai, T., Nelson, G.S., Guy, F. and Rogers, R. (1972) Studies with Brugia paltangi—I. Parasitological observations on primary infections of cats (Felis catus). International Journal for Parasitology, 2, 239–247.CrossRefGoogle ScholarPubMed
Dhar, D.N. and Singha, P. (1971) Studies on quantitative infections of Litomosoides carinii (Travassos, 1919) in white rats. Zeitschrift für Tropenmedizin und Parasitologie, 22, 312–325.Google Scholar
Hawking, F. (1967) The 24-hour periodicity of microfilariae: biological mechanisms responsible for its production and control. Proceedings of the Royal Society of London B. Biological Sciences, 169, 59–76.Google Scholar
Ho, B.C, Singh, M. and Yap, E.H. (1974) Population dynamics of mjcrofilarial production and eosinophil levels in slow Iorises infected with Breinlia sergenti, Petter (Filarioidea: Dipetalonematidae). International Journal for Parasitology, 4, 383–388.Google Scholar
Ho, B.C., Singh, M., Yap, E.H. and Lim, B.L. (1975) Studies on the Malayan forest rat filaria, Breinlia booliati (Filarioidea: Onchocercidae): Transmission to laboratory rats. International Journal for Parasitology (In press).Google Scholar
Ho, B.C., Singh, M., Yap, E.H., and Lim, E.P.C. (1975) Studies on the Malayan forest rat filaria, Breinlia booliati (Filarioidea: Onchocercidae): Relative susceptibility of various species of mosquitoes. (Submitted for Publication).Google Scholar
Kershaw, W.E. (1949) Observations on Litomosoides carinii (Travassos, 1919) Chandler, 1931 III—The first-stage larva in the peripheral circulation. Annals of tropical Medicine and Parasitology, 43, 238–259.CrossRefGoogle Scholar
Laing, A.B.G. (1961) The influence of the host on the periodicity of the microfilariae of B. malayi. Transactions of the Royal Society of Tropical Medicine and Hygiene, 55, 558.Google Scholar
Pacheco, G. and Orihel, T.C. (1968) Relationship between detectable microfilaria and total population of microfilariae in monkeys infected with Dirofilaria corynodes. Journal of Parasitology, 54, 1234–1235.Google Scholar
Singh, M. and Ho, B.C. (1973) Breinlia booliati sp.n. (Filarioidea: Onchocercidae) a filaria of the Malayan forest rat, Rattus sabanus (Thos). Journal of Helminthology, 47, 127–133.Google Scholar
Singh, M., Ho, B.C. and Lim, B.L. (1972) Preliminary results on experimental transmission of a new filarial parasite, Breinlia booliati sp.n. Singh and Ho, 1972 from Malayan wild rats to laboratory albino rat. Southeast Asian Journal of Tropical Medicine and Public Health, 3, 622.Google Scholar
Wilson, T. and Ramachandran, C.P. (1971) Brugia infections in man and animals: Long-term observations on microfilaraemia and estimates of the efficiency of transmission from mosquito vector to definitive host. Annals of tropical Medicine and Parasitology, 65, 525–546.CrossRefGoogle ScholarPubMed
Zaman, V. and Chellappah, W.T. (1968) Studies on vector susceptibility and larval morphology of a filaria of the slow loris, Nycticebus coucang. Annals of tropical Medicine and Parasitology, 62, 450–454.Google Scholar