Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-28T20:32:47.953Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies on Dracunculus medinensis (Linnaeus) I. The Early Migration Route in Experimentally Infected Dogs

Published online by Cambridge University Press:  05 June 2009

Ralph Muller
Ralph Muller
Affiliation:
Department of Parasitology, London School of Hygiene and Tropical Medicine
Get access Rights & Permissions [Opens in a new window]

Extract

1. Ten dogs were given infective larvae of Dracunculus medinensis, originally from human cases in Western Nigeria, and bred in the laboratory in Cyclops leuckarti (Claus).

2. Parasites were found in seven of the dogs when dissected at intervals between 4 hours and 36 days. From an examination of the location of the larvae obtained, both by direct search and by the use of intravenous Evans' blue, it was concluded that they migrated directly through the tissues via the intestinal wall (about 13 hours), abdominal mesenteries (found at 7 and 10 days), and muscles of the abdominal and thoracic wall (15 days). A similar route of migration is believed to take place in cats from an examination of three positive kittens.

3. Almost no increase in length of the larvae occurred during the migration; these measured an average of 0·59 mm. in length after 15 days.

4. No moult was observed up to 36 days but one may have been missed.

Type
Research Article
Information
Journal of Helminthology , Volume 42 , Issue 3-4 , September 1968 , pp. 331 - 338
Copyright
Copyright © Cambridge University Press 1968

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Buckley, J. J. C., and Edeson, J. F. B., 1956.—“On the adult morphology of Wuchereria sp. (malayi?) from a monkey (Macaca irus) and from cats in Malaya, and on Wuchereria pahangi n.sp. from a dog and a cat.” J. Helminth., 30, 1–20.CrossRefGoogle ScholarPubMed
Edeson, J. F. B. and Buckley, J. J. C., 1959.—“Studies on filariasis in Malaya:on the migration and rate of growth of Wuchereria malayi in experimentally infected cats.” Ann. trop. Med. Parasit., 53, 113–119.CrossRefGoogle ScholarPubMed
Fedchenko, A. P., 1871.—Invest. Imp. Obsh. Llub. Estestrozn., Moskva 1869/70. 8, 71–82.Google Scholar
Issajev, L. M., 1934.—Med. Parasitol., Moscow. 3, 231–238.Google Scholar
Moorthy, V. N., 1937.—“A redescription of Dracunculus medinensis.” J. Parasit., 23, 220–224.CrossRefGoogle Scholar
Moorthy, V. N., and Sweet, W. C., 1936.—“A note on the experimental infection of dogs with dracontiasis.” Ind. med. Gaz., 71, 437–451.Google ScholarPubMed
Moorthy, V. N., and Sweet, W. C., 1938.—“Further notes on the experimental infection of dogs with dracontiasis.” Am. J. Hyg., 27, 301–310.Google Scholar
Onabamiro, S. D., 1950.—“A technique for studying infection of Dracunculus in Cyclops.” Nature, Lond., 165, 31.CrossRefGoogle Scholar
Onabamiro, S. D., 1951.—“The transmission of Dracunculus medinensis by Thermocyclops nigerianus, as observed in a village in South-West Nigeria.” Ann. trop. Med. Parasit., 45, 1–10.CrossRefGoogle Scholar
Onabamiro, S. D., 1956.—“The early stage of the development of Dracunculus medinensis (Linnaeus) in the mammalian host.” Ann. trop. Med. Parasit., 50, 157–166.CrossRefGoogle ScholarPubMed
Platzer, E., 1966.—Proc. 1st Internat. Congr. Parasitology (Rome, 1964) p. 561. Pergamon Press,Milan.Google Scholar
Scott, J. A., MacDonald, E. M. and Terman, B., 1951.—“A description of the stages in the life cycle of the filarial worm Litomosoides carinii.” J. Parasit., 37, 425–432.CrossRefGoogle ScholarPubMed