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Studies on amphistomiasis in Andhra Pradesh (India) VI. Immunization of lambs and kids with gamma irradiated metacercariae of Cercariae indicae XXVI

Published online by Cambridge University Press:  05 June 2009

Md. Hafeez  and
B. V. Rao
Md. Hafeez
Affiliation:
Department of Parasitology, College of Veterinary Science, Tirupati (A.P.), India
B. V. Rao
Affiliation:
Department of Parasitology, College of Veterinary Science, Tirupati (A.P.), India
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Abstract

The life span and the pathogenicity of amphistomes developing from Cercariae indicae XXVI (Paramphistomum epiclitum) were considerably reduced when the metacercariae were gamma-irradiated at 2krad or 3krad. The higher irradiation dose resulted in the complete absence of the flukes in infected animals. Single vaccination of lambs and kids with 3000 metacercariae irradiated at 2 krad or 3 krad stimulated a significant degree of resistance against challenge with 5000 non-irradiated metacercariae. The resistance was more pronounced in the group vaccinated with metacercariae irradiated at 3krad.

Type
Research Article
Information
Journal of Helminthology , Volume 55 , Issue 1 , March 1981 , pp. 29 - 32
Copyright
Copyright © Cambridge University Press 1981

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References

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