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Observations on the Resistance to Schistosome Infection of Neonatal Mice born to Immune Mothers with a Demonstration of Increased Resistance in Lactating Mice

Published online by Cambridge University Press:  05 June 2009

M. G. Taylor ,
D. A. Denham  and
G. S. Nelson
M. G. Taylor
Affiliation:
Medical Helminthology Department, London School of Hygiene and Tropical Medicine
D. A. Denham
Affiliation:
Medical Helminthology Department, London School of Hygiene and Tropical Medicine
G. S. Nelson
Affiliation:
Medical Helminthology Department, London School of Hygiene and Tropical Medicine
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Extract

An attempt was made to demonstrate passive transfer of immunity using neonatal mice born to mothers resistant to schistosome infection. No immunity was demonstrated in the baby mice, suggesting that the classes of antibody which are active in this immune system are not transferrable neonatally.

An interesting incidental finding was the apparent enhanced resistance of lactating mice compared to normal females or males and this was confirmed in another experiment. There was no significant difference between the susceptibility of normal females and male mice. More male worms were recovered from male mice than from virgin female mice.

Type
Research Article
Information
Journal of Helminthology , Volume 45 , Issue 2-3 , June 1971 , pp. 223 - 228
Copyright
Copyright © Cambridge University Press 1971

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References

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