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Global prevalence of Strongyloides stercoralis in dogs: A systematic review and meta-analysis

Published online by Cambridge University Press:  21 February 2022

Tahmineh Gorgani-Firouzjaee Open the ORCID record for Tahmineh Gorgani-Firouzjaee [Opens in a new window] ,
Narges Kalantari Open the ORCID record for Narges Kalantari [Opens in a new window] ,
Mohammad Chehrazi ,
Salman Ghaffari Open the ORCID record for Salman Ghaffari [Opens in a new window]  and
Shaysteh Shahdin
Tahmineh Gorgani-Firouzjaee
Affiliation:
Department of Mycology and Parasitology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Narges Kalantari*
Affiliation:
Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Mohammad Chehrazi
Affiliation:
Department of Biostatistics and Epidemiology, School of Health Science, Babol University of Medical Sciences, Babol, Iran
Salman Ghaffari
Affiliation:
Department of Mycology and Parasitology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Shaysteh Shahdin
Affiliation:
Department of Laboratory Sciences, Faculty of Paramedical Sciences, Babol University of Medical Sciences, Babol, Iran
*
Author for correspondence: Narges Kalantari, Fax.: +981132 238 284. E mail: [email protected]
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Abstract

Strongyloides stercoralis is an intestinal parasitic helminth that mainly affects humans and dogs throughout the world. Canine strongyloidosis is generally characterized by asymptomatic infection, with fatal disease in cases of immunodeficiency. This study was conducted in order to evaluate the global prevalence of S. stercoralis in dogs. Six electronic databases were searched for this purpose. The random effects model and 95% confidence intervals (CI) were applied to determine the overall and subgroup pooled prevalence. Heterogeneity was assessed by Cochran's Q test and I2 statistic. In total, 56 datasets from 50 studies from 1,202 peer-reviewed papers were included in the current meta-analysis. 20,627 dogs were assessed in 27 countries across six World Health Organization (WHO) regions. The global prevalence of S. stercoralis infection among dogs was 6% (95% CI 4–8%; 868/20,627). According to WHO regions, the estimated prevalence ranges 2% to 11% as follows: Western Pacific (11%, 0–31%); Africa (9%, 2–19%); America (6%, 3–11%); South-East Asia (5%, 1–13%)’ Europe (3%, 2–5%); and Eastern Mediterranean (2%, 0–6%). The pooled prevalence of S. stercoralis infection in dog owners was 7% (1–18%). The prevalence of S. stercoralis infection in studies based on serological assays was significantly higher than other techniques (29%, 20–39%). Younger female dogs, less than one year old, from rural areas had higher prevalence rates than their male counterparts, with no statistically significant differences. From this review, it is concluded that the low global prevalence of S. stercoralis in dogs may be strongly associated with low sensitivity diagnostic methods applied in most studies leading to the underestimation of infection rates. Therefore, the improvement of diagnostic techniques is recommended for precise evaluation of the disease.

Keywords

CanineprevalenceStrongyloides stercoralis
Type
Review Article
Information
Journal of Helminthology , Volume 96 , 2022 , e11
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press

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