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Experimental ancylostomiasis in Swiss albino mice: adrenal and thyroid histopathology

Published online by Cambridge University Press:  05 June 2009

Ismail Bhai  and
A. K. Pandey
Ismail Bhai
Affiliation:
Endocrinology Unit, School of Studies in Zoology, Vikram University, Ujjain 456010, India
A. K. Pandey
Affiliation:
Endocrinology Unit, School of Studies in Zoology, Vikram University, Ujjain 456010, India
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Abstract

Remarkable hypertrophic changes were observed in the adrenal and thyroid glands of male mice after 7 to 16 days of infection with the filariform larvae of Ancylostoma caninum, but not in females. The adrenal gland revealed enormous enlargement of cells in the zonae glomerulosa, fasciculata and medulla, and also the formation of big vacuoles in the glomerular zone, whereas the thyroid gland showed distinctly hypcrtrophicd follicular epithelium with marked acolloidal condition and follicular mass formation. These changes in the cellular diameter were highly significant (P>0·001 to <0·005). The possible reasons for hyperactivity of these glands are discussed.

Type
Research Article
Information
Journal of Helminthology , Volume 55 , Issue 4 , December 1981 , pp. 295 - 305
Copyright
Copyright © Cambridge University Press 1981

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