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Cytochemical observations on cholinergic, serotoninergic and peptidergic neuronal pathways in Cephalochlamys namaquensis

Published online by Cambridge University Press:  05 June 2009

D. M. Mckay ,
D. W. Halton ,
C. F. Johnston ,
C. Shaw  and
I. Fairweather
D. M. Mckay
Affiliation:
Comparative Neuroendocrinology Research Group, Schools of Biology & Biochemistry and Clinical Medicine, The Queen's University of Belfast, Belfast BT7 INN, UK
D. W. Halton*
Affiliation:
Comparative Neuroendocrinology Research Group, Schools of Biology & Biochemistry and Clinical Medicine, The Queen's University of Belfast, Belfast BT7 INN, UK
C. F. Johnston
Affiliation:
Comparative Neuroendocrinology Research Group, Schools of Biology & Biochemistry and Clinical Medicine, The Queen's University of Belfast, Belfast BT7 INN, UK
C. Shaw
Affiliation:
Comparative Neuroendocrinology Research Group, Schools of Biology & Biochemistry and Clinical Medicine, The Queen's University of Belfast, Belfast BT7 INN, UK
I. Fairweather
Affiliation:
Comparative Neuroendocrinology Research Group, Schools of Biology & Biochemistry and Clinical Medicine, The Queen's University of Belfast, Belfast BT7 INN, UK
*
*Author to whom correspondence should be addressed.
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Abstract

The localization and distribution of cholinergic, serotoninergic (5-HT, serotonin) and peptidergic components of the nervous system of adult Cephalochlamys namaquensis (Cestoda: Pseudophyllidea) have been determined using enzyme histochemical and immunocytochemical techniques interfaced with light and confocal scanning laser microscopy. All three classes of neuroactive substance showed a similar pattern of staining, occurring extensively throughout the central and peripheral nervous systems of the parasite. There were some minor regional differences in staining, suggesting specific roles for certain classes of neurone, and nerve cell bodies were most evident following immunostaining for serotonin. The general overlap in the distribution of staining may be indicative of some co-localization of neurotransmitter and/or neuromodulatory substances.

Keywords

Cephalochlamys namaquensischolinesteraseserotonin (=5-HT)neuropeptidesimmunocytochemistryCestoda
Type
Research Article
Information
Journal of Helminthology , Volume 66 , Issue 3 , September 1992 , pp. 205 - 212
Copyright
Copyright © Cambridge University Press 1992

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