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Attempts to infect small laboratory animals with the infective larvae of Onchocerca lienalis

Published online by Cambridge University Press:  05 June 2009

S. Townson
Affiliation:
London School of Hygiene ami Tropical Medicine, Winches Farm Field Station, 395 Hat field Road, St. A Ibans, Hertfordshire, ALA OXQ. UK
Dawn Owen
Affiliation:
London School of Hygiene ami Tropical Medicine, Winches Farm Field Station, 395 Hat field Road, St. A Ibans, Hertfordshire, ALA OXQ. UK

Extract

All the natural hosts of Onchocerca parasites are large animals (MULLI-R, 1979) andthere is, therefore an urgent need to develop a small animal model for onchoccrciasis,preferably one that employs a strain of inbred host. Rodents have been usedsuccessfully as experimental hosts for the microfilariac of O. guiturosa (sec NELSON et al. 1966), O. cervicalis (see RAbalais, 1974), O. armilluta (see EL Bihari & Hussein, 1975) and O. ijibsoni (see Beveridge et al., 1980) but there have been few publishedattempts to infect these hosts with infective-stage larvae.

Type
Research Note
Copyright
Copyright © Cambridge University Press 1981

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