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Is small placenta a risk for low birth weight in KOKAN? (Data from a coastal region in the state of Maharashtra, India)

Published online by Cambridge University Press:  03 August 2020

Suvarna Patil Open the ORCID record for Suvarna Patil [Opens in a new window] ,
Vijay Dombale ,
Charudatta Joglekar ,
Netaji Patil ,
Kiran Joshi ,
Bhushan Warpe  and
Pushpa Burute
Suvarna Patil*
Affiliation:
Department of Medicine, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun District-Ratnagiri, Maharashtra, India
Vijay Dombale
Affiliation:
Department of Pathology, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun, District-Ratnagiri, Maharashtra, India
Charudatta Joglekar
Affiliation:
Statistics Unit, Regional Centre for Adolescent Health and Nutrition, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun, District-Ratnagiri, Maharashtra, India
Netaji Patil
Affiliation:
Department of Radiology, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun, District-Ratnagiri, Maharashtra, India
Kiran Joshi
Affiliation:
Department Obstetrics and Gynaecology, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun, District-Ratnagiri, Maharashtra, India
Bhushan Warpe
Affiliation:
Department of Pathology, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun, District-Ratnagiri, Maharashtra, India
Pushpa Burute
Affiliation:
Department of Anatomy, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun, District-Ratnagiri, Maharashtra, India
*
Address for correspondence: Suvarna Patil, Department of Medicine, BKL Walawalkar Hospital and Rural Medical College, Sawarde, Taluka-Chiplun District-Ratnagiri, Maharashtra415606, India. Email: [email protected]
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Abstract

KOKAN region is characterized by undernutrition across all stages of lifecycle. Developmental Origins of Health & Disease hypothesis suggests that environmental influences in the early period of growth and development can contribute to the risks of noncommunicable diseases (NCD) in adulthood. Newborns and placentas of 815 pregnant mothers delivered in a rural hospital were studied. We tested the hypothesis that low placental weight will be associated with low birth weight (LBW). Mothers had a mean age of 26 years and were smaller in size at delivery [mean height of 152.1 cm (±6.1 cm), weight 52 kg (±10.2 kg), body mass index (BMI) 22.5 kg/m2 (±4.1 kg/m2)]. Mean placental weight was 488 g (±120 g). Mean birth weight, length, and head circumference of the newborn were 2.54 kg (±0.5 kg), 46.3 cm (±3.1 cm), and 32.7 cm (±1.7 cm), respectively. Prevalence of LBW, stunting, and small head size was 41.6%, 42.2%, and 18.2%, respectively. Maternal height, weight, and BMI at delivery were all positively associated with placental weight (p < 0.01 for all). Mothers with placentas in the lowest placental weight tertile had an increased likelihood of producing an LBW baby [OR 7.7, 95% CI (5.0, 11.8)], a stunted baby [OR 1.9 (1.4, 2.9)], or a baby with a small head circumference [OR 2.4 (1.4, 4.0)]. Mothers in the lowest height tertile had odds of producing a LBW baby [OR 1.8 95% CI (1.2, 2.7)] or a stunted baby [OR 1.6 (1.1, 2.3)]. There is a need to improve the nutritional status of women in KOKAN region which may reduce the risk of NCD.

Keywords

Placentabirth weightunderweightstuntingrural
Type
Original Article
Information
Journal of Developmental Origins of Health and Disease , Volume 12 , Issue 4 , August 2021 , pp. 652 - 659
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Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2020

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References

Afodun, AM, Ajao, MS, Enaibe, BU. Placental anthropometric features: maternal and neonate characteristics in North Central Nigeria. Adv Anat. 2015; 2015, 790617.Google Scholar
Balihallimath, RL, Shirol, VS, Gan, AM, Tyagi, NK, Bandankar, MR. Placentalmorphometry determines the birth weight. J Clin Diagn Res. 2013; 7, 2428–2431.Google ScholarPubMed
Gluckman, PD, Hanson, MA, Living with the past: evolution, development, and patterns of disease. Science. 2004; 305, 1733–1736.CrossRefGoogle ScholarPubMed
Gluckman, PD, Hanson, MA, Cooper, C, Thornburg, KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008; 359, 61–73.CrossRefGoogle ScholarPubMed
Barker, DJ. The long-term outcome of retarded fetal growth. Clin Obstet Gynecol. 1997; 40, 853–863.CrossRefGoogle ScholarPubMed
Barker, DJ. The malnourished baby and infant. Br Med Bull. 2001; 60: 69–88.CrossRefGoogle ScholarPubMed
Cetin, I, Alvino, G,Radaelli, T, Pardi, G. Fetal nutrition: a review. Acta Paediatr. 2005; 94, 7–13.CrossRefGoogle ScholarPubMed
Haggarty, P. Placental regulation of fatty acid delivery and its effect on fetal growth—a review. Placenta. 2002; 23(Suppl A), S28–S38.CrossRefGoogle ScholarPubMed
Sibley, CP, Turner, MA, Cetin, I, et al. Placental phenotypes of intrauterine growth. Pediatr Res. 2005; 58, 827–32.CrossRefGoogle ScholarPubMed
Constancia, M, Angiolini, I, Sandovici, I, et al. Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci USA. 2005; 102, 19219–19224.CrossRefGoogle ScholarPubMed
Odorisio, T, Cianfarani, F, Failla, CM, Zambruno, G. The placenta growth factor in skin angiogenesis. J Dermatol Sci. 2006; 41, 11–19.CrossRefGoogle ScholarPubMed
Lauritzen, L, Carlson, SE. Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status. Matern Child Nutr. 2011; 7(Suppl 2), 41–58.CrossRefGoogle ScholarPubMed
Patil, S, Kadam, S, Desai, M, et al. Diabetes in KOKAN region of India. World J Diabetes. 2019; 10, 37–46.Google Scholar
Pevekar, KS, Patil, SN, Chavan, AJ. Psychsocial study of adolescent girls from rural Konkan region (Maharashtra). Int J Res Med Sci 2015; 3: 2745–2750.CrossRefGoogle Scholar
Patil, SN, Wasnik, VR, Wadke, R. Health problems amongst adolescent girls in rural areas of Ratnagiri district of Maharashtra, India. J Clin Diag Res. 2009; 3: 1784–1790.Google Scholar
Patil, S, Joglekar, C, Desai, M, et al. Nutritional status and psychological impairment in rural adolescent girls: pilot data from “KOKAN” Region of Western India. Front Public Health. 2018; 6, 160.CrossRefGoogle ScholarPubMed
Patil, S. Holistic antenatal care for rural areas- challenges and solutions. Int J Curr Res. 2017; 9, 53151–53153.Google Scholar
International Institute of Population Sciences. National Family Health Survey, India: Key Findings from NFHS-4. Available from: http://rchiips.org/nfhs/factsheet_NFHS-4.shtml Google Scholar
Scherle, WF. A simple method for volumetry of organ in quantitative stereology. Mikroskopie. 1970; 26, 57–60.Google ScholarPubMed
The WHO Child Growth Standards. http://www.who.int/childgrowth/standards/en/. Accessed October 1, 2018.Google Scholar
Leary, S, Fall, C, Osmond, C, et al. Geographical variation in neonatal phenotype. Acta Obstet Gynecol Scand. 2006; 85, 1080–1089.CrossRefGoogle ScholarPubMed
Roland, MC, Friis, CM, Voldner, N, et al. Fetal growth versus birthweight: the role of placenta versus other determinants. PLoS One. 2012; 7, e39324.CrossRefGoogle ScholarPubMed
Risnes, KR, Romundstad, PR, Nilsen, TI, et al. Placental weight relative to birth weight and long-term cardiovascular mortality: findings from a cohort of 31,307 men and women. Am J Epidemiol. 2009; 170, 622–631.CrossRefGoogle ScholarPubMed
Thame, M, Osmond, C, Bennett, F, et al. Fetal growth is directly related to maternal anthropometry and placental volume. Eur J Clin Nutr. 2004; 58, 894–900.CrossRefGoogle ScholarPubMed
Kinare, AS, Natekar, AS, Chinchwadkar, MC, et al. Low midpregnancy placental volume in rural Indian women: a cause for low birth weight? Am J Obstet Gynecol. 2000; 182, 443–448.CrossRefGoogle ScholarPubMed
Soliman, AT, Eldabbagh, M, Saleem, W, et al. Placental weight: relation to maternal weight and growth parameters of full-term babies at birth and during childhood. J Trop Pediatr. 2013; 59, 358–364.CrossRefGoogle ScholarPubMed
Sivarao, S, Vidyadaran, MK, Jammal, AB, et al. Weight, volume and surface area of placenta of normal pregnant women and their relation to maternal and neonatal parameters in Malay, Chinese and Indian ethnic groups. Placenta. 2002; 23, 691–696.CrossRefGoogle ScholarPubMed
Winder, NR, Krishnaveni, GV, Veena, SR, et al. Mother’s lifetime nutrition and the size, shape and efficiency of the placenta. Placenta. 2011; 32, 806–810.CrossRefGoogle ScholarPubMed
Winder, NR, Krishnaveni, GV, Hill, JC, et al. Placental programming of blood pressure in Indian children. Acta Paediatr. 2011; 100, 653–660.CrossRefGoogle ScholarPubMed
Ravikumar, G, Crasta, J, Prabhu, JS, et al. Eccentric placentae have reduced surface area and are associated with lower birth weight in babies small for gestational age. J Dev Orig Health Dis. 2018; 9, 281–286.CrossRefGoogle ScholarPubMed
Ravikumar, G, Crasta, J, Prabhu, JS, et al. CD15 as a marker of fetoplacental endothelial immaturity in IUGR placentas. J Matern Fetal Neonatal Med. 2019; 32, 1646–1653.CrossRefGoogle ScholarPubMed
Jaya, DS, Kumar, NS, Bai, LS. Anthropometric indices, cord length and placental weight in newborns. Indian Pediatr. 1995; 32, 1183–1188.Google ScholarPubMed
DiPietro, JA, Voegtline, KM. The gestational foundation of sex differences in development and vulnerability. Neuroscience 2017; 342, 4–20.CrossRefGoogle ScholarPubMed
Sood, R, Zehnder, JL, Druzin, ML, et al. Gene expression patterns in human placenta. Proc Natl Acad Sci U S A. 2006; 103(14), 5478–5483.CrossRefGoogle ScholarPubMed
McCormick, MC. The contribution of low birth weight to infant mortality and childhood morbidity. N Engl J Med. 1985; 312, 82–90.CrossRefGoogle Scholar
Barker, DJ. Fetal origins of coronary heart disease. BMJ. 1995; 311, 171–174.CrossRefGoogle ScholarPubMed
Roseboom, TJ, van der Meulen, JH, Osmond, C, et al. Coronary heart disease after prenatal exposure to the Dutch famine, 1944–45. Heart 2000; 84, 595–598.CrossRefGoogle ScholarPubMed
Lawlor, DA, Ronalds, G, Clark, H, et al. Birth weight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: findings from the Aberdeen Children of the 1950s prospective cohort study. Circulation 2005; 112, 1414–1418.CrossRefGoogle ScholarPubMed
Barker, DJ. Birth weight and hypertension. Hypertension 2006; 48, 357–358.CrossRefGoogle ScholarPubMed
Launer, LJ, Hofman, A, Grobbee, DE. Relation between birth weight and blood pressure: longitudinal study of infants and children. BMJ 1993; 307, 1451–1454.CrossRefGoogle ScholarPubMed
Koupilová, I, Leon, DA, McKeigue, PM, et al. Is the effect of low birth weight on cardiovascular mortality mediated through high blood pressure? J Hypertens. 1999; 17, 19–25.CrossRefGoogle ScholarPubMed
Law, CM, Egger, P, Dada, O et al. Body size at birth and blood pressure among children in developing countries. Int J Epidemiol. 2001; 30, 52–57.CrossRefGoogle ScholarPubMed
Hales, CN, Barker, DJ, Clark, PM, et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991; 303, 1019–1022.CrossRefGoogle ScholarPubMed
Lithell, HO, McKeigue, PM, Berglund, L, et al. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 1996; 312, 406–410.CrossRefGoogle ScholarPubMed
Rich-Edwards, JW, Colditz, GA, Stampfer, MJ, et al. Birthweight and the risk for type 2 diabetes mellitus in adult women. Ann Intern Med. 1999; 130: 278–284.CrossRefGoogle ScholarPubMed
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