Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-17T17:10:04.268Z Has data issue: false hasContentIssue false
  • English
  • Français

Female ponderal index at birth and idiopathic infertility

Part of: DOHaD on International Women's Day 2020

Published online by Cambridge University Press:  16 July 2019

Charlotte Dupont ,
Audrey Hulot ,
Florence Jaffrezic ,
Céline Faure ,
Sébastien Czernichow ,
Nathalie di Clemente ,
Chrystele Racine ,
Pascale Chavatte-Palmer ,
Rachel Lévy  and
Alifert group
Charlotte Dupont*
Affiliation:
Sorbonne Université, Saint Antoine Research center, INSERM équipe Lipodystrophies génétiques et acquises. Service de biologie de la reproduction-CECOS, AP-HP, Hôpital Tenon, F-75020 Paris, France
Audrey Hulot
Affiliation:
UMR GABI, AgroParisTech, INRA, Université Paris-Saclay, 78350Jouy-en-Josas, France UMR Mia-Paris, AgroParisTech, INRA, Université Paris-Saclay, 75005Paris, France Inserm U1173, Simone Veil School of Health Sciences, University of Versailles Saint-Quentin-en-Yvelines, Montigny-le-Bretonneux, France
Florence Jaffrezic
Affiliation:
UMR GABI, AgroParisTech, INRA, Université Paris-Saclay, 78350Jouy-en-Josas, France
Céline Faure
Affiliation:
Service de biologie de la reproduction-CECOS, APHP, Hôpital Tenon, Paris, France
Sébastien Czernichow
Affiliation:
Service de nutrition (Centre Spécialisé Obésité), Hôpital Européen Georges-Pompidou, APHP Paris, France Université Paris Descartes, ParisFrance
Nathalie di Clemente
Affiliation:
Centre de Recherche Saint-Antoine (CRSA), Sorbonne Université-INSERM, 75012Paris, France Institut Hospitalo-Universitaire ICAN, 75013Paris, France
Chrystele Racine
Affiliation:
Centre de Recherche Saint-Antoine (CRSA), Sorbonne Université-INSERM, 75012Paris, France Institut Hospitalo-Universitaire ICAN, 75013Paris, France Université de Paris, Saint Antoine Research center, INSERM équipe Lipodystrophies génétiques et acquises, F-75012 Paris, France
Pascale Chavatte-Palmer
Affiliation:
UMR BDR, INRA, ENVA, Université Paris Saclay, 78350, Jouy en Josas, France
Rachel Lévy
Affiliation:
Sorbonne Université, Saint Antoine Research center, INSERM équipe Lipodystrophies génétiques et acquises. Service de biologie de la reproduction-CECOS, AP-HP, Hôpital Tenon, F-75020 Paris, France
*
Address for correspondence: Charlotte Dupont, Saint Antoine Research center, INSERM équipe Lipodystrophies génétiques et acquises, Sorbonne Université and Service de biologie de la reproduction-CECOS, AP-HP, Hôpital Tenon, F-75020 Paris, France. Email: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Epidemiological studies have demonstrated an increased risk of developing non-transmittable diseases in adults subjected to adverse early developmental conditions. Metabolic and cardiovascular diseases have been the focus of most studies. Nevertheless, data from animal models also suggest early programming of fertility. In humans, it is difficult to assess the impact of the in utero environment retrospectively. Birthweight is commonly used as an indirect indicator of intrauterine development. This research is part of the ALIFERT study. We investigated a potential link between ponderal index at birth and female fertility in adulthood. Data from 51 infertile and 74 fertile women were analysed. BW was on average higher in infertile women, whereas birth length did not differ between the two groups; thus, resulting in a significantly higher ponderal index at birth in infertile women. Ponderal index at birth has been identified as a risk factor for infertility. These results suggest the importance of the intra-uterine environment, not only for long-term metabolic health but also for fertility.

Keywords

ponderal indexbirthweightfemale fertilityfemale infertility
Type
Brief Report
Information
Journal of Developmental Origins of Health and Disease , Volume 11 , Issue 2 , April 2020 , pp. 154 - 158
Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Alifert Collaborative Group: Isabelle Aknin: Unité fonctionnelle de biologie de la reproduction, histologie – embryologie – cytogénétique, hôpital Nord, Saint-Étienne, France ; Isabelle Cedrin-Durnerin: Service de Médecine de la Reproduction, Hôpital Jean Verdier, APHP, Bondy, France ; Steven Cens, Centre d’AMP de PAU, Polyclinique de Navarre, Pau, France; Serge Hercberg: EREN, INSERM U557; INRA; CNAM; Université Paris 13, CRNH IdF, 93017 Bobigny, France; Khaled Pocate: Service d’Histologie-Embryologie-Biologie de la Reproduction, Hôpital Cochin APHP, Paris, France; Nathalie Sermondade: Service de biologie de la reproduction-CECOS, Hôpital Tenon, APHP, Paris, France ; Claude Uthurriague, Centre d’AMP de PAU, Polyclinique de Navarre, Pau ; Jean-Philippe Wolf: Service d’Histologie-Embryologie-Biologie de la Reproduction, Hôpital Cochin, APHP, Paris, France

References

Hanson, MA, Gluckman, PD.Early developmental conditioning of later health and disease: physiology or pathophysiology? Physiol Rev. 2014; 94, 1027–1076.CrossRefGoogle ScholarPubMed
Rae, MT, Palassio, S, Kyle, CE, et al.Effect of maternal undernutrition during pregnancy on early ovarian development and subsequent follicular development in sheep fetuses. Reproduction. 2001; 122, 915–922.CrossRefGoogle ScholarPubMed
Bernal, AB, Vickers, MH, Hampton, MB, Poynton, RA, Sloboda, DM.Maternal undernutrition significantly impacts ovarian follicle number and increases ovarian oxidative stress in adult rat offspring. PLoS One. 2010; 5, e15558.CrossRefGoogle ScholarPubMed
Da Silva, P, Aitken, RP, Rhind, SM, Racey, PA, Wallace, JM.Impact of maternal nutrition during pregnancy on pituitary gonadotrophin gene expression and ovarian development in growth-restricted and normally grown late gestation sheep fetuses. Reproduction. 2002; 123, 769–777.CrossRefGoogle ScholarPubMed
Chadio, S, Kotsampasi, B.The role of early life nutrition in programming of reproductive function. J Dev Orig Health Dis. 2014; 5, 2–15.CrossRefGoogle ScholarPubMed
Winship, AL, Gazzard, SE, Cullen McEwen, LA, Bertram, JF, Hutt, KJ.Maternal low protein diet programmes low ovarian reserve in offspring. Reproduction. 2018; 156, 299–311.CrossRefGoogle ScholarPubMed
Tom, SE, Cooper, R, Kuh, D, et al.Fetal environment and early age at natural menopause in a British birth cohort study. Hum Reprod. 2010; 25, 791–798.CrossRefGoogle Scholar
Cresswell, JL, Egger, P, Fall, CH, et al.Is the age of menopause determined in-utero? Early Hum Dev. 1997; 49, 143–148.CrossRefGoogle ScholarPubMed
Nohr, EA, Vaeth, M, Rasmussen, S, Ramlau-Hansen, CH, Olsen, J.Waiting time to pregnancy according to maternal birthweight and prepregnancy BMI. Hum Reprod. 2009; 24, 226–232.CrossRefGoogle ScholarPubMed
Ibanez, L, Potau, N, Ferrer, A, et al.Anovulation in eumenorrheic, nonobese adolescent girls born small for gestational age: insulin sensitization induces ovulation, increases lean body mass, and reduces abdominal fat excess, dyslipidemia, and subclinical hyperandrogenism. J Clin Endocrinol Metab. 2002; 87, 5702–5705.CrossRefGoogle ScholarPubMed
Pandolfi, C, Zugaro, A, Lattanzio, F, et al.Low birth weight and later development of insulin resistance and biochemical/clinical features of polycystic ovary syndrome. Metabolism. 2008; 57, 999–1004.CrossRefGoogle ScholarPubMed
Borghese, B, Sibiude, J, Santulli, P, et al.Low birth weight is strongly associated with the risk of deep infiltrating endometriosis: results of a 743 case-control study. PLoS One. 2015; 10, e0117387.CrossRefGoogle ScholarPubMed
Cooley, SM, Donnelly, JC, Walsh, T, et al.Ponderal index (PI) vs birth weight centiles in the low-risk primigravid population: which is the better predictor of fetal wellbeing? J Obstet Gynaecol. 2012; 32, 439–443.CrossRefGoogle ScholarPubMed
Howe, LD, Tilling, K, Benfield, L, et al.Changes in ponderal index and body mass index across childhood and their associations with fat mass and cardiovascular risk factors at age 15. PLoS One. 2010; 5, e15186.CrossRefGoogle ScholarPubMed
Davies, MJ, March, WA, Willson, KJ, Giles, LC, Moore, VM.Birthweight and thinness at birth independently predict symptoms of polycystic ovary syndrome in adulthood. Hum Reprod. 2012; 27, 1475–1480.CrossRefGoogle ScholarPubMed
Faure, C, Dupont, C, Chavatte-Palmer, P, et al.Are semen parameters related to birth weight? Fertil Steril. 2015; 103, 6–10.CrossRefGoogle ScholarPubMed
Deveci, SE, Deveci, F, Acik, Y, Ozan, AT.The measurement of exhaled carbon monoxide in healthy smokers and non-smokers. Respir Med. 2004; 98, 551–556.CrossRefGoogle ScholarPubMed
Maga, M, Janik, MK, Wachsmann, A, et al.Influence of air pollution on exhaled carbon monoxide levels in smokers and non-smokers. A prospective cross-sectional study. Environ Res. 2017; 152, 496–502.CrossRefGoogle ScholarPubMed
Chen, LW, Tint, MT, Fortier, MV, et al.Which anthropometric measures best reflect neonatal adiposity? Int J Obes (Lond). 2018; 42, 501–506.CrossRefGoogle ScholarPubMed
Crusell, M, Damm, P, Hansen, T, et al.Ponderal index at birth associates with later risk of gestational diabetes mellitus. Arch Gynecol Obstet. 2017; 296, 249–256.CrossRefGoogle ScholarPubMed
Chavatte-Palmer, P, Rousseau-Ralliard, D, Tarrade, A.Oxidative stress in mammals: pregnancy and placental function. In Oxidative Stress and Women’s Health (ed Menezo, Y), 2016. Eska editions, Paris.Google Scholar
Tarrade, A, Panchenko, P, Junien, C, Gabory, A.Placental contribution to nutritional programming of health and diseases: epigenetics and sexual dimorphism. J Exp Biol. 2015; 218, 50–58. doi: 10.1242/jeb.110320. ReviewCrossRefGoogle ScholarPubMed
Michalakis, K, Mintziori, G, Kaprara, A, Tarlatzis, BC, Goulis, DG.The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review. Metabolism. 2013; 62, 457–478.CrossRefGoogle ScholarPubMed
Puttabyatappa, M, Padmanabhan, V.Developmental programming of ovarian functions and dysfunctions. Vitam Horm. 2018; 107, 377–422.CrossRefGoogle ScholarPubMed
Miska, EA, Ferguson-Smith, AC.Transgenerational inheritance: models and mechanisms of non-DNA sequence-based inheritance. Science. 2016; 354, 59–63.CrossRefGoogle ScholarPubMed
Leveille, P, Tarrade, A, Dupont, C, et al.Maternal high-fat diet induces follicular atresia but does not affect fertility in adult rabbit offspring. J Dev Orig Health Dis. 2014; 5, 88–97.CrossRefGoogle Scholar
Yarde, F, Broekmans, FJ, van der Pal-de Bruin, KM, et al.Prenatal famine, birthweight, reproductive performance and age at menopause: the Dutch hunger winter families study. Hum Reprod. 2013; 28, 3328–3336.CrossRefGoogle ScholarPubMed
Tarry-Adkins, JL, Martin-Gronert, MS, Chen, JH, Cripps, RL, Ozanne, SE.Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats. FASEB J. 2008; 22, 2037–2044.CrossRefGoogle ScholarPubMed
Krisher, RL.Maternal age affects oocyte developmental potential at both ends of the age spectrum. Reprod Fertil Dev. 2019; 31, 1–9CrossRefGoogle Scholar
Foucaut, AM, Faure, C, Julia, C, et al.Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women. PLoS One. 2019; 14, e0210770.CrossRefGoogle ScholarPubMed
Barouki, R, Gluckman, PD, Grandjean, P, Hanson, M, Heindel, JJ.Developmental origins of non-communicable disease: implications for research and public health. Environ Health. 2012; 11, 42.CrossRefGoogle ScholarPubMed