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Difference between body composition of formula- and breastfed infants at birth

Published online by Cambridge University Press:  28 May 2019

Hazel Ann Smith Open the ORCID record for Hazel Ann Smith [Opens in a new window] ,
Jonathan O’B Hourihane ,
Louise C. Kenny ,
Mairead Kiely ,
P. Leahy-Warren ,
Darren L. Dahly  and
Deirdre M. Murray
Hazel Ann Smith*
Affiliation:
Paediatrics & Child Health, University College Cork, Cork, Ireland
Jonathan O’B Hourihane
Affiliation:
Paediatrics & Child Health, University College Cork, Cork, Ireland Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland
Louise C. Kenny
Affiliation:
Department of Women’s and Children’s Health, Faculty of Health and Life Sciences, University of Liverpool, England
Mairead Kiely
Affiliation:
Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland School of Food and Nutritional Sciences, University College Cork, Cork, Ireland
P. Leahy-Warren
Affiliation:
School of Nursing & Midwifery, University College, Cork, Ireland
Darren L. Dahly
Affiliation:
HRB Clinical Research Facility – Cork, University College, Cork, Ireland School of Public Health, University College Cork, Cork, Ireland
Deirdre M. Murray
Affiliation:
Paediatrics & Child Health, University College Cork, Cork, Ireland Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland
*
Address for correspondence: Hazel Ann Smith, Paediatrics & Child Health, University College Cork, Cork, Ireland. Email: author [email protected]
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Abstract

Breastfeeding may reduce obesity risk, but this association could be confounded by breastfeeding families’ characteristics. We investigated if body composition differs at birth among infants who were either exclusively breast- or formula-fed. We hypothesized the two groups would differ in body composition, even at birth, prior to their post-natal feeding experience. Healthy primiparous carrying singleton pregnancy were recruited at 15 weeks’ gestation. PEA POD® measured body composition within 72 hours of delivery and infant feeding was prospectively captured. Out of the 1,152 infants recruited, 117 (10.2%) and 239 (20.7%) went on to be either exclusively breast- or formula-fed, respectively. Breastfed infants were heavier at birth, but their percentage fat mass (FM) was lower than that of exclusively formula-fed infants (covariate adjusted β = −1.91 percentage points of FM; 95% CI −2.82 to −1.01). Differences in intra-uterine exposures, irrespective of early diet, may partly explain an infant’s obesity risk.

Keywords

Body compositionbreastfeedingobesity
Type
Brief Report
Information
Journal of Developmental Origins of Health and Disease , Volume 10 , Issue 6 , December 2019 , pp. 616 - 620
Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2019 

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